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Table 2 Summary baseline table of studies comparing AIAT vs. IIAT

From: Pseudomonas infections among hospitalized adults in Latin America: a systematic review and meta-analysis

Author Year

Country (Enrollment Period)

Study Design

Total Follow-up

Total N

Pathogen

Site of Infection

Mean Age (SD), yr

% Male

% IIAT

Timeliness of AIAT

Susceptibility reported

Araujo 2016 [12]

Brazil (2009–2012; 2014–2014)

CC

~ 55 days

236

MDR and Non-MDR PA

BSI: 100%

52.7 (22.9)

70.3

36

< 24 h

Yes

Dantas 2014 [15]

Brazil (2009–2011)

RC

~ 55.4 days

120

Resistant and susceptible PA

BSI: 100%

51.5 (3.2)

63.3

28.3

NR

NR

Gonzales 2014 [13]

Colombia (2005–2008)

RC; CC

30 days

164

PA

RS: 37.5%; Central venous catheter 28.6%

56 (33.5)

67.1

50

< 48 h

Yes

Pinheiro 2008 [17]

Brazil (2006–2007)

RC; CC

30 days

131

PA

RS: 65.6%; BSI: 18.3%; UTI: 11.5%

64.2 (18.4)

50.4

37.3

NR

Yes

Tuon 2012 [16]

Brazil (2006–2009)

CC

30 days

77

CRPA, CSPA

BSI: 100%

48.0

72.7

52

< 24 h

Yes

Rossi 2017 [14]

Brazil (2009–2012)

CC

NR

157

PA 100%

Unknown: 62.42; RS: 17.19; BSI: 13.37

52.0 (24.5)

66.9

31.2

NR

Yes

  1. AIAT Appropriate initial antibiotic therapy; BSI Bacteremia/Bloodstream infection; CC Case-control; CRPA Carbapenem-resistant Pseudomonas aeruginosa; CSPA Carbapenem-susceptible Pseudomonas aeruginosa; H hour; IIAT Inappropriate initial antibiotic therapy; MDR Multidrug resistant; N Number; NR Not reported; PA Pseudomonas aeruginosa; RC Retrospective; RS Respiratory; UTI Urinary tract infection; Yr Year