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Table 2 ALT and HBV-DNA level before and after transsphenoidal surgery with prophylactic NA administration

From: Case reports of latent HBV hepatitis in patients after neurosurgical treatment for hypothalamic and pituitary tumors

No.

HBV-DNA level before NA administration (log IU/ml)

ALT before NA (IU/l)

HBV-DNA level before surgery (log IU/ml)

ALT before surgery (IU/l)

Duration of steroid administration after surgery

Types of NA

Duration of NA administration before surgery

Duration of NA administration after surgery

1

2.1

27

not available

23

19 days

lamivudine

14 days

6 weeks

2

> 8.3

911

not detected

194

3 days

entecavir

22 days

2 years

3

2.6

24

not detected

19

2 days

entecavir

224 days

continued

4

not detected

18

not detected

16

continued

entecavir

14 days

continued

5

2.3

57

not detected

48

continued

tenofovir

23 days

continued

  1. HBV hepatitis B virus, DNA deoxyribonucleic acid, NA nucleot(s)ide analogues, ALT alanine aminotransferase