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Table 5 Odds ratios for risk factors associated with lipodystrophy, Myanmar, 2016

From: High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar

 

Lipodystrophy

Hypertriglyceridemia

OR (95% CI)

aOR (95% CI)

p-value

OR (95% CI)

aOR (95% CI)

p-value

Sex

 Female

ref

ref

 

ref

ref

 

 Male

1.0 (0.6–1.8)

0.80 (0.4–1.6)

0.589

1.1 (0.5–2.4)

0.9 (0.4–2.2)

0.768

Age (years) at ART start

0.8 (0.8–0.9)

0.9 (0.8–1.0)

0.059

1.0 (0.9–1.1)

1.1 (1.0–1.3)

0.067

WHO status at cohort entry

 1

ref

ref

 

ref

ref

 

 2

1.7 (0.7–4.0)

1.2 (0.4–3.1)

0.729

0.6 (0.2–1.8)

0.5 (0.2–1.5)

0.213

 3

1.9 (0.9–4.3)

2.1 (0.8–5.4)

0.117

0.6 (0.2–1.5)

0.3 (0.1–1.0)

0.055

 4

0.8 (0.2–3.6)

0.9 (0.2–5.0)

0.921

0.7 (0.1–3.7)

0.4 (0.1–2.8)

0.350

Exposure to D4T-based regimen1

 No

ref

ref

 

ref

ref

 

 Yes

19 (2.5–142)

11 (1.3–92)

0.028

5.5 (0.7–42)

8.1 (0.9–73)

0.061

Exposure to AZT-based regimen1

 No

ref

ref

 

ref

ref

 

 Yes

2.1 (1.1–4.2)

1.7 (0.6–4.3)

0.290

1.0 (0.4–2.4)

3.3 (1.0–10.3)

0.042

Exposure to PI-based (LPV) regimen1

 No

ref

ref

 

ref

ref

 

 Yes

2.0 (1.0–4.1)

1.3 (0.4–3.8)

0.645

3.7 (1.6–8.3)

7.7 (2.2–26.8)

0.001

Exposure to EFV-based regimen1

 No

ref

ref

 

ref

ref

 

 Yes

0.3 (0.2–0.7)

0.5 (0.2–1.3)

0.161

0.6 (0.3–1.4)

2.3 (0.7–7.4)

0.148

  1. 1Exposure is considered at least six months of treatment with the drug