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Table 3 Cox regression analysis of predictors of tuberculosis among cohorts of PLHIV on chronic HIV car at Debre-Markos Referral Hospital from January 1, 2014 to December 31, 2018 (n = 494)

From: Incidence and predictors of tuberculosis occurrence among adults on antiretroviral therapy at Debre Markos referral hospital, Northwest Ethiopia: retrospective follow-up study

VariableSurvival statusCHR (95% CI)Adjusted
EventCensoredAHR (95% CI)P-value
Past TB treatment
 Yes682.84 (1.22, 6.64)1.01 (0.38, 2.69)0.981
 No564241.001.00 
HIV disclosure
 Disclosed7300.59 (0.27, 1.30)0.74 (0.31, 1.76)0.495
 Not disclosed554021.001.00 
WHO staging
 I/II133301.001.00 
 III37857.55 (4.01, 14.22)1.27 (0.59, 2.71)0.534
 IV121713.37 (6.09, 29.36)2.18 (0.86, 5.52)0.100
CD4 count (cells/μl)
  ≤ 2004711711.28 (4.48, 26.36)2.31 (0.85, 6.30)0.101
 201–350101133.04 (1.04, 8.89)1.34 (0.43, 4.17)0.608
  ≥ 35052021.001.00 
Hemoglobin level
  < 10 g/dl528314.41 (7.32, 28.38)5.25 (2.52,10.95)<  0.001*
  ≥ 10 g/dl103491.001.00 
BMI (kg/m2)
  < 18.5471147.51 (4.19, 13.44)1.97 (0.99, 3.88)0.052
  ≥ 18.5153181.001.00 
Functional status
 Working153771.001.00 
 Ambulatory/bedridden475514.10 (7.87, 25.28)2.31 (1.13, 4.73)0.021*
ART adherence
 Good153521.001.00 
 Fair /poor47809.76 (5.45, 17.47)3.22 (1.64, 6.31)0.001*
Took IPT
 Yes51900.13 (0.05, 0.31)0.33 (0.12, 0.85)0.023*
 No572421.001.00 
  1. * Independently significant predictors of TB at p-value < 0.05