Table 3 Cox regression analysis of predictors of tuberculosis among cohorts of PLHIV on chronic HIV car at Debre-Markos Referral Hospital from January 1, 2014 to December 31, 2018 (n = 494)
Variable | Survival status | CHR (95% CI) | Adjusted | ||
|---|---|---|---|---|---|
Event | Censored | AHR (95% CI) | P-value | ||
Past TB treatment | |||||
Yes | 6 | 8 | 2.84 (1.22, 6.64) | 1.01 (0.38, 2.69) | 0.981 |
No | 56 | 424 | 1.00 | 1.00 | |
HIV disclosure | |||||
Disclosed | 7 | 30 | 0.59 (0.27, 1.30) | 0.74 (0.31, 1.76) | 0.495 |
Not disclosed | 55 | 402 | 1.00 | 1.00 | |
WHO staging | |||||
I/II | 13 | 330 | 1.00 | 1.00 | |
III | 37 | 85 | 7.55 (4.01, 14.22) | 1.27 (0.59, 2.71) | 0.534 |
IV | 12 | 17 | 13.37 (6.09, 29.36) | 2.18 (0.86, 5.52) | 0.100 |
CD4 count (cells/μl) | |||||
≤ 200 | 47 | 117 | 11.28 (4.48, 26.36) | 2.31 (0.85, 6.30) | 0.101 |
201–350 | 10 | 113 | 3.04 (1.04, 8.89) | 1.34 (0.43, 4.17) | 0.608 |
≥ 350 | 5 | 202 | 1.00 | 1.00 | |
Hemoglobin level | |||||
< 10 g/dl | 52 | 83 | 14.41 (7.32, 28.38) | 5.25 (2.52,10.95) | < 0.001* |
≥ 10 g/dl | 10 | 349 | 1.00 | 1.00 | |
BMI (kg/m2) | |||||
< 18.5 | 47 | 114 | 7.51 (4.19, 13.44) | 1.97 (0.99, 3.88) | 0.052 |
≥ 18.5 | 15 | 318 | 1.00 | 1.00 | |
Functional status | |||||
Working | 15 | 377 | 1.00 | 1.00 | |
Ambulatory/bedridden | 47 | 55 | 14.10 (7.87, 25.28) | 2.31 (1.13, 4.73) | 0.021* |
ART adherence | |||||
Good | 15 | 352 | 1.00 | 1.00 | |
Fair /poor | 47 | 80 | 9.76 (5.45, 17.47) | 3.22 (1.64, 6.31) | 0.001* |
Took IPT | |||||
Yes | 5 | 190 | 0.13 (0.05, 0.31) | 0.33 (0.12, 0.85) | 0.023* |
No | 57 | 242 | 1.00 | 1.00 | |