Can metagenomic next-generation sequencing identify the pathogens responsible for culture-negative prosthetic joint infection?

Table 1 Demographic characteristics of the EA and TA groups

Variable	EA group (n = 12)	TA group (n = 12)	P value
Sex, male	3	8	0.1^*
Age (years)	60.67 ± 14.705	70.67 ± 13.296	0.095^***
Joint, hip	9	6	0.4^**
BMI (kg/m²)	24.46 ± 4.217	25.16 ± 4.30	0.71^***
CCI	3	3.83	0.68^***
Sinus	15	7	1^**
CRP	38.3 ± 63.883	63.49 ± 34.163	0.891^***
ESR	68.92 ± 38.901	63.49 ± 42.324	0.747^***
Aspirate WBCs (/cmm)	5834 (2219–14,818)	9441.5 (1100–31,810)	0.091^****
Aspirate neutrophils (%)	83.30 ± 11.531	81.01 ± 15.08	0.681^***
Tsukayama type
II	5	3
IV	7	9	0.667^**
Follow-up (month)	39 (34–44)	18.5 (12–32)	0.001^****

BMI body mass index, ASA American Society of Anesthesiologists, CCI Charlson Comorbidity Index, CRP C-reactive protein, ESR erythrocyte sedimentation rate, WBC white blood cell
^*Chi-square test; ^**Fisher’s exact test; ^***Student’s t-test; ^****Mann-Whitney U-test

ISSN: 1471-2334