Burden of Staphylococcus aureus infections after orthopedic surgery in Germany

BMC Infectious Diseases

Table 5 Generalized linear model of total costs within 365 days follow-up period

*Variable*	*Coef.*	*exp(b)*	*p-value*	*95% CI* *of exp (b)*
Age at index	0.01	1.01	< 0.001	1.00–1.01
Sex
Male	Reference
Female	−0.16	0.85	< 0.001	0.82–0.87
Index surgery type
Hip	Reference
Knee	−0.06	0.94	0.002	0.90–0.97
Spine	0.03	1.04	0.066	0.99–1.07
CCI (12 months baseline period)	0.09	1.10	< 0.001	1.09–1.10
Length of index hospitalization in days	0.01	1.01	< 0.001	1.00–1.00
Complications due to prosthetic devices/ implants/grafts during index hospitalization	0.19	1.21	< 0.001	1.14–1.29
**S. aureusinfection within 365 days after surgery**	0.66	1.93	< 0.001	1.73–2.13
Recent fractures at the location of index surgery (3 months baseline period)	0.78	2.19	< 0.001	2.10–2.27
Bacterial infections (not caused by any Staphylococci) during index hospitalization	0.67	1.96	< 0.001	1.83–2.10
Number of outpatient prescriptions of antibiotics (12 months baseline period)	0.03	1.03	< 0.001	1.01–1.03

Number of subjects = 74,327
CCI Charlson Comorbidity Index, CI Confidence interval, Coef Coefficient, S aureus, Staphylococcus aureus

ISSN: 1471-2334