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Table 4 All-cause mortality, HCRU and costs after orthopedic surgery in patients with/without S. aureus infection

From: Burden of Staphylococcus aureus infections after orthopedic surgery in Germany

 

Patients with SAI in the 365-d follow-up

Patients w/o SAI in the 365-d follow-up

p-value for differences between patients with/without SAI

N

1430

72,897

 

Patients who died

 During index hospital stay,%

0

1.27

p < 0.001

 Within 30 d, %

0.35

1.40

p < 0.001

 Within 90 d, %

4.90

2.79

p < 0.001

 Within 180 d, %

11.61

3.91

p < 0.001

 Within 365 d, %

22.38

5.31

p < 0.001

365-d follow-up HCRU per patient-year

 No. of outpatient GP visits, Mean (SD)

3.17

3.20

p = 0.566

 No. of outpatient specialist visits, Mean (SD)

3.65

3.46

p < 0.001

 No. of all-cause hospitalizations, Mean (SD) a

3.06

0.70

p < 0.001

 No. of hospital days, Mean (SD) a

53.48

6.92

p < 0.001

 No. of outpatient prescriptions of antibiotics, Mean (SD)

2.17

0.63

p < 0.001

365-d follow-up costs (€) per patient-year

 Outpatient physician visits

1149€

1011€

p < 0.001

 Outpatient all-agent medication

2605€

1327€

p < 0.001

 Hospitalizations (incl. Inpatient drug treatment) b

39,080€

11,444€

p < 0.001

 Total costs

42,834€

13,781€

p < 0.001

  1. Outcomes measured within 365 days after index surgical procedure, censoring at time of death
  2. S aureus, Staphylococcus aureus, SAI Staphylococcus aureus infection, SD Standard deviation
  3. aExcluding index hospitalization; bIncluding index hospitalization