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Table 3 Univariable and multivariable analysis of factors associated with ICU admissiona in patients with VRE bloodstream infection

From: Epidemiology, treatment and outcomes of bloodstream infection due to vancomycin-resistant enterococci in cancer patients in a vanB endemic setting

 ICU admission (n = 13)No ICU admission
(n = 80)
Univariable odds ratio95% CIp-valueMultivariable odds ratio95% CIp-value
Age, median (IQR), years47 (40–63)58 (43–66)0.980.94–1.010.212   
Male6 (46%)43 (54%)0.740.23–2.390.612   
CDS-VRE, median (IQR)1.9 (1.5–3.6)1.9 (1.8–3.4)1.020.67–1.550.932   
Hematological malignancy12 (92%)69 (86%)1.910.23–16.210.552   
AlloBMT6 (46%)18 (23%)2.950.88–9.900.0800.960.16–5.960.968
Antibiotic days prior to BSI, median (IQR)20 (18–29)16 (9–26)1.030.99–1.080.1631.020.97–1.080.399
ICU admissionb4 (31%)25 (31%)0.980.28–3.480.972   
Hypoalbuminemia daysb, median (IQR)18 (14–30)17 (9–29)1.030.97–1.090.380   
Mucositis grade, median (IQR)3 (0–4)0 (0–2)1.601.11–2.300.0111.811.04–3.140.036
Polymicrobial BSI3 (23%)18 (23%)1.030.26–4.160.963   
Neutropenia at time of BSI9 (69%)66 (83%)0.480.13–1.770.269   
Teicoplanin monotherapy4 (31%)55 (69%)0.230.06–0.830.0240.140.03–0.660.013
  1. CDS-VRE score Chronic Disease Score specific to VRE, CKD chronic kidney disease, AML Acute myeloid leukemia, alloBMT allogeneic bone marrow transplant
  2. aICU admission within 48-h of bloodstream infection
  3. bIn 30 days prior to bloodstream infection