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Table 1 Comparison of clinical and laboratory characteristics in children admitted with malaria with and without Sickle cell disease

From: Malaria in patients with sickle cell anaemia: burden, risk factors and outcome at the Laquintinie hospital, Cameroon

Characteristics

SCD n = 276

Non SCD n = 2857

tests statistics

 

n

%

n

%

Chi-square

p-value

Température ≥40 °C

104

37,7%

275

9,6%

186

< 0.001*

Prostration (yes)

209

75,7%

592

20,7%

395

< 0.001*

Convulsion (yes)

10

3,6%

204

7,1%

4,89

0.03*

Hepatomegaly (yes)

74

26,8%

140

4,9%

162

< 0.001*

Splenomegaly (yes)

86

31,2%

155

5,4%

235

< 0.001*

Haemoglobinuria (yes)

9

3,3%

86

3,0%

0,054

0,817

Jaundice (yes)

46

16,7%

26

0,9%

243

< 0.001*

Respiratory distress (yes)

42

15,2%

326

11,4%

3,52

0,061

Impaired consciousness (yes)

8

2,9%

218

7,6%

8,42

0.004*

Hb level < 5 g/dL

104

37,7%

191

6,7%

280

< 0.001*

WBC > 15 (× 109 cells/L)

140

50,7%

173

6,1%

558

< 0.001*

Parasite density > 250,000 or 5%

5

1,8%

136

4,8%

5,09

0.024*

 

mean

SD

mean

SD

t-value

p-value

Hb level (g/dL)

5,7

2,6

7,4

1,4

17,47

< 0.001*

Leucocyte count (× 109 cells/L)

20,3

10,9

9,8

5,6

26,66

0,394

Platelet count (cells/mm3)

274,014

175,135

177,668

98,578

14,21

< 0.001*

Parasite density (parasites/uL)

54,546

13,760

88,543

27,053

20,62

< 0.001*

  1. * statistically significant at p <  0.05
  2. Values in boldface are set at less than or equal to 0.05