Table 2 Sensitivity and specificity of each diagnostic test using the composite reference standard and culture of either lymph node tissue or FNA
From: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis
Tuberculosis test | Sensitivity against composite reference | Specificity against composite reference | Sensitivity against culture | Specificity against culture |
|---|---|---|---|---|
AFBs on FNA (n = 61) | 7/27; 26% (11–46) | 34/34; 100% (90–100) | 3/8; 38% (9–76) | 49/53; 92% (82–98) |
FNA culture (n = 17) | 4/12; 33% (10–65) | 5/5; 100% (48–100) | 4/4; 100% (40–100) | 13/13; 100% (75–100) |
AFBs on tissue (n = 81) | 8/24; 33% (16–55) | 57/57; 100% (94–100) | 4/10; 40% (12–74) | 67/71; 94% (86–98) |
Tissue culture (n = 75) | 9/23; 39% (20–61) | 52/52; 100% (93–100) | 9/10; 90% (55–100) | 65/65; 100% (94–100) |
Necrotising granulomas on histology (n = 81) | 20/24; 83% (63–95) | 55/57; 96% (88–100) | 10/10; 100% (69–100) | 59/71; 83% (72–91) |