Skip to main content

Table 2 Sensitivity and specificity of each diagnostic test using the composite reference standard and culture of either lymph node tissue or FNA

From: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Tuberculosis testSensitivity against composite referenceSpecificity against composite referenceSensitivity against cultureSpecificity against culture
AFBs on FNA (n = 61)7/27; 26% (11–46)34/34; 100% (90–100)3/8; 38% (9–76)49/53; 92% (82–98)
FNA culture (n = 17)4/12; 33% (10–65)5/5; 100% (48–100)4/4; 100% (40–100)13/13; 100% (75–100)
AFBs on tissue (n = 81)8/24; 33% (16–55)57/57; 100% (94–100)4/10; 40% (12–74)67/71; 94% (86–98)
Tissue culture (n = 75)9/23; 39% (20–61)52/52; 100% (93–100)9/10; 90% (55–100)65/65; 100% (94–100)
Necrotising granulomas on histology (n = 81)20/24; 83% (63–95)55/57; 96% (88–100)10/10; 100% (69–100)59/71; 83% (72–91)
  1. Data are n/N; % (95% CI). FNA Fine-needle aspirate, AFBs Acid fast bacilli, PPV Positive predictive value, NPV Negative predictive value