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Table 1 Baseline characteristics by diagnostic group

From: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

 Total (n = 99)Definite TB (n = 21)Probable TB (n = 15)Not TB (n = 63)P-value
Sex
 Males45 (45%)9 (43%)4 (27%)32 (51%)0.233
 Females54 (55%)12 (57%)11 (73%)31 (49%) 
Age (median [IQR])37 (30–49)32 (28–35)36 (31–41)44 (32–57)0.003
 HIV status
 Positive50 (51%)13 (62%)8 (53%)29 (46%)0.442
 Negative49 (49%)8 (38%)7 (47%)34 (54%) 
On ARVS31 (62%)8 (62%)7 (88%)16 (55%)0.263
CD4 count (cells/mm3, median [IQR])216 (82–361)100 (55–254)351 (88–497)252 (92–361)0.106
 < 10016 (32%)6 (46%)2 (25%)8 (28%)0.675
 100–24910 (20%)3 (23%)1 (13%)6 (21%) 
 ≥ 25024 (48%)4 (31%)5 (63%)15 (52%) 
Performance Score
 ECOG 049 (50%)10 (48%)9 (60%)30 (48%)0.979
 ECOG 128 (28%)6 (29%)5 (33%)17 (27%) 
 ECOG 24 (4%)1 (5%)03 (5%) 
 ECOG 316 (16%)4 (19%)1 (7%)11 (17%) 
 ECOG 42 (2%)002 (3%) 
Patient Type
 Inpatient16 (16%)4 (19%)2 (13%)10 (16%)0.924
 Outpatient83 (84%)17 (81%)13 (87%)53 (84%) 
Previous tuberculosis24 (24%)6 (29%)6 (40%)12 (19%)0.205
On tuberculosis treatment21 (21%)6 (29%)6 (40%)9 (15%)0.059
Consistency of lymph node
 Firm81 (87%)16 (80%)12 (86%)53 (90%)0.491
 Fluctuant12 (13%)4 (20%)2 (14%)6 (10%) 
Symptoms
 Cough27 (27%)6 (29%)3 (20%)18 (29%)0.79
 Weight loss47 (47%)13 (62%)5 (33%)29 (46%)0.222
 Night sweats29 (29%)8 (38%)3 (20%)18 (29%)0.49
Location of lymph nodes
 Unilateral61 (62%)13 (62%)12 (80%)36 (57%)0.262
 Bilateral38 (38%)8 (38%)3 (20%)27 (43%) 
Lymph node FNA/biopsy site
 Neck85 (86%)19 (90%)14 (93%)52 (83%)0.881
 Axilla10 (10%)2 (10%)1 (7%)7 (11%) 
 Inguinal4 (4%)004 (6%) 
Blood results (median [IQR])
 LDH (units/L)267 (218–341)292 (251–341)218 (194–239)273 (230–366)0.006
 Hb (g/dL)12.1 (9.4–13.4)10.5 (8.7–12.1)11.8 (9.6–12.7)12.4 (9.7–13.5)0.041
 WCC (cells × 10^9)6.9 (4.9–9.1)5.3 (4.0–8.0)5.7 (4.8–7.3)7.4 (5.2–9.9)0.142
 Lymphocytes (cells × 10^9)1.7 (1.0–2.4)1.2 (0.7–1.9)1.7 (1.4–2.0)1.7 (1.0–2.7)0.197
  1. P values <0.05 are shown in bold. Data are n/N; % (95% CI). ECOG Eastern Cooperative Oncology Group, LDH Lactate Dehydrogenase, Hb Haemoglobin, WCC White Cell Count