ELISA is superior to bacterial culture and agglutination test in the diagnosis of brucellosis in an endemic area in China

Table 4 Sensitivity, Specificity, True Positive and True Negative values of various tests

	Sensitivity (95%CI)	Specificity(95% CI)	PPA (95%CI)	NPA (95%CI)
Culture	0.217 (0.167,0.276)	1.000 (0.981,1.000)	1.000 (0.913,1.000)	0.574 (0.526,0.621)
STA	0.638 (0.573,0.0.699)	0.935 (0.895,0.961)	0.903 (0.845,0.942)	0.732 (0.679,0.779)
IgM by ELISA	0.609 (0.543,0.671)	0.984 (0.956,0.995)	0.972 (0.927,0.991)	0.726 (0.675,0.773)
IgG by ELISA	0.961 (0.926,0.981)	1.000 (0.981,1.000)	1.000 (0.979,1.000)	0.964 (0.932,0.983)
IgM + IgG by ELISA	0.987 (0.960,0.997)	0.984 (0.956,0.995)	0.983 (0.954,0.994)	0.987 (0.962,0.997)

Note: STA: standard tube agglutination. PPA: positive percent agreement. NPA:negative percent agreement

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