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Table 5 Top 10 genes in gene co-expression network in 3 cohorts

From: Bioinformatics analysis on multiple Gene Expression Omnibus datasets of the hepatitis B virus infection and its response to the interferon-alpha therapy

RankGene symbolGene descriptionDegree
Cohort 1
 1CD2CD2 molecule17
 2HLA-DMAmajor histocompatibility complex, class II, DM alpha15
 3LCKlymphocyte-specific protein tyrosine kinase14
 4CCND2cyclin D212
 5CD8ACD8a molecule12
 6ITKIL2-inducible T-cell kinase11
 7JAK3Janus kinase 311
 8CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity10
 9RASGRP1RAS guanyl releasing protein 110
 10CXCR4chemokine (C-X-C motif) receptor 49
Cohort 2
 1HLA-DMAmajor histocompatibility complex, class II, DM alpha28
 2CD2CD2 molecule28
 3CD74CD74 molecule, major histocompatibility complex, class II invariant chain26
 4CD8ACD8a molecule24
 5CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity24
 6LCKlymphocyte-specific protein tyrosine kinase24
 7CCND2cyclin D223
 8JAK3Janus kinase 323
 9CXCR4chemokine (C-X-C motif) receptor 423
 10RASGRP1RAS guanyl releasing protein21
Cohort 3
 1APOBapolipoprotein B26
 2NME7NME/NM23 family member 725
 3LMAN1lectin, mannose-binding, 124
 4CDH1cadherin 1, type 1, E-cadherin (epithelial)23
 5CD46CD46 molecule, complement regulatory protein23
 6PRKACBprotein kinase, cAMP-dependent, catalytic, beta22
 7SCARB2scavenger receptor class B, member 220
 8SSH1slingshot protein phosphatase 119
 9PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 118
 10ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 1118