Table 5 Top 10 genes in gene co-expression network in 3 cohorts
Rank | Gene symbol | Gene description | Degree |
|---|---|---|---|
Cohort 1 | |||
 1 | CD2 | CD2 molecule | 17 |
 2 | HLA-DMA | major histocompatibility complex, class II, DM alpha | 15 |
 3 | LCK | lymphocyte-specific protein tyrosine kinase | 14 |
 4 | CCND2 | cyclin D2 | 12 |
 5 | CD8A | CD8a molecule | 12 |
 6 | ITK | IL2-inducible T-cell kinase | 11 |
 7 | JAK3 | Janus kinase 3 | 11 |
 8 | CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity | 10 |
 9 | RASGRP1 | RAS guanyl releasing protein 1 | 10 |
 10 | CXCR4 | chemokine (C-X-C motif) receptor 4 | 9 |
Cohort 2 | |||
 1 | HLA-DMA | major histocompatibility complex, class II, DM alpha | 28 |
 2 | CD2 | CD2 molecule | 28 |
 3 | CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 26 |
 4 | CD8A | CD8a molecule | 24 |
 5 | CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity | 24 |
 6 | LCK | lymphocyte-specific protein tyrosine kinase | 24 |
 7 | CCND2 | cyclin D2 | 23 |
 8 | JAK3 | Janus kinase 3 | 23 |
 9 | CXCR4 | chemokine (C-X-C motif) receptor 4 | 23 |
 10 | RASGRP1 | RAS guanyl releasing protein | 21 |
Cohort 3 | |||
 1 | APOB | apolipoprotein B | 26 |
 2 | NME7 | NME/NM23 family member 7 | 25 |
 3 | LMAN1 | lectin, mannose-binding, 1 | 24 |
 4 | CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 23 |
 5 | CD46 | CD46 molecule, complement regulatory protein | 23 |
 6 | PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 22 |
 7 | SCARB2 | scavenger receptor class B, member 2 | 20 |
 8 | SSH1 | slingshot protein phosphatase 1 | 19 |
 9 | PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 | 18 |
 10 | ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 18 |