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Table 5 Top 10 genes in gene co-expression network in 3 cohorts

From: Bioinformatics analysis on multiple Gene Expression Omnibus datasets of the hepatitis B virus infection and its response to the interferon-alpha therapy

Rank Gene symbol Gene description Degree
Cohort 1
 1 CD2 CD2 molecule 17
 2 HLA-DMA major histocompatibility complex, class II, DM alpha 15
 3 LCK lymphocyte-specific protein tyrosine kinase 14
 4 CCND2 cyclin D2 12
 5 CD8A CD8a molecule 12
 6 ITK IL2-inducible T-cell kinase 11
 7 JAK3 Janus kinase 3 11
 8 CSF2RB colony stimulating factor 2 receptor, beta, low-affinity 10
 9 RASGRP1 RAS guanyl releasing protein 1 10
 10 CXCR4 chemokine (C-X-C motif) receptor 4 9
Cohort 2
 1 HLA-DMA major histocompatibility complex, class II, DM alpha 28
 2 CD2 CD2 molecule 28
 3 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 26
 4 CD8A CD8a molecule 24
 5 CSF2RB colony stimulating factor 2 receptor, beta, low-affinity 24
 6 LCK lymphocyte-specific protein tyrosine kinase 24
 7 CCND2 cyclin D2 23
 8 JAK3 Janus kinase 3 23
 9 CXCR4 chemokine (C-X-C motif) receptor 4 23
 10 RASGRP1 RAS guanyl releasing protein 21
Cohort 3
 1 APOB apolipoprotein B 26
 2 NME7 NME/NM23 family member 7 25
 3 LMAN1 lectin, mannose-binding, 1 24
 4 CDH1 cadherin 1, type 1, E-cadherin (epithelial) 23
 5 CD46 CD46 molecule, complement regulatory protein 23
 6 PRKACB protein kinase, cAMP-dependent, catalytic, beta 22
 7 SCARB2 scavenger receptor class B, member 2 20
 8 SSH1 slingshot protein phosphatase 1 19
 9 PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 18
 10 ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 18