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Table 4 Top 10 genes in gene signal network in 3 cohorts

From: Bioinformatics analysis on multiple Gene Expression Omnibus datasets of the hepatitis B virus infection and its response to the interferon-alpha therapy

RankGene symbolGene descriptionDegree
Cohort 1
 1ENTPD1ectonucleoside triphosphate diphosphohydrolase 156
 2TYMSthymidylate synthetase30
 3PLA2G2Aphospholipase A2, group IIA28
 4PLD3phospholipase D family, member 324
 5PPAP2Bphosphatidic acid phosphatase type 2B22
 6CDKN1Acyclin-dependent kinase inhibitor 1A8
 7CCR2chemokine (C-C motif) receptor 27
 8CXCR4chemokine (C-X-C motif) receptor 47
 9AKT1v-akt murine thymoma viral oncogene homolog 15
 10CCL5chemokine (C-C motif) ligand 54
Cohort 2
 1ENTPD1ectonucleoside triphosphate diphosphohydrolase 156
 2TYMSthymidylate synthetase30
 3ACTBactin, beta28
 4ACTN4actinin, alpha 424
 5PLA2G2Aphospholipase A2, group IIA22
 6PLD3phospholipase D family, member 316
 7PPAP2Bphosphatidic acid phosphatase type 2B10
 8CDKN1Acyclin-dependent kinase inhibitor 1A8
 9PIP4K2Aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha7
 10CCR2chemokine (C-C motif) receptor 26.5
Cohort 3
 1PRKACBprotein kinase, cAMP-dependent, catalytic, beta18
 2EP300E1A binding protein p30018
 3ADCY1adenylate cyclase 118
 4CREB1cAMP responsive element binding protein 117
 5STAT1signal transducer and activator of transcription 115
 6CTNNB1catenin (cadherin-associated protein), beta 1, 88 kDa15
 7ITGB5integrin, beta 515
 8PRKCBprotein kinase C, beta14
 9STAT3signal transducer and activator of transcription 312
 10AKT2v-akt murine thymoma viral oncogene homolog 210