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Table 3 Top 20 pathways by KEGG pathway analysis in 3 cohorts

From: Bioinformatics analysis on multiple Gene Expression Omnibus datasets of the hepatitis B virus infection and its response to the interferon-alpha therapy

Rank Cohort 1 Cohort 2 Cohort 3
1 Chemokine signaling pathway Chemokine signaling pathway PI3K-Akt signaling pathway
2 Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction Influenza A
3 Focal adhesion Focal adhesion Metabolic pathways
4 PI3K-Akt signaling pathway PI3K-Akt signaling pathway Cytokine-cytokine receptor interaction
5 HTLV-I infection HTLV-I infection Chemokine signaling pathway
6 Metabolic pathways Metabolic pathways HTLV-I infection
7 ECM-receptor interaction Cell adhesion molecules (CAMs) Herpes simplex infection
8 Cell adhesion molecules (CAMs) ECM-receptor interaction Toxoplasmosis
9 p53 signaling pathway p53 signaling pathway Hematopoietic cell lineage
10 Rheumatoid arthritis Amoebiasis Protein processing in endoplasmic reticulum
11 Viral carcinogenesis Proteoglycans in cancer NF-kappa B signaling pathway
12 Amoebiasis Viral carcinogenesis Insulin signaling pathway
13 Protein digestion and absorption Rheumatoid arthritis Leukocyte transendothelial migration
14 Proteoglycans in cancer Influenza A Focal adhesion
15 NF-kappa B signaling pathway Protein digestion and absorption Phagosome
16 Cell cycle Hepatitis B Measles
17 Pathways in cancer NF-kappa B signaling pathway Adipocytokine signaling pathway
18 Toll-like receptor signaling pathway Fc gamma R-mediated phagocytosis Antigen processing and presentation
19 Influenza A Cell cycle Adherens junction
20 Hepatitis B Malaria Leishmaniasis
  1. KEGG Kyoto Encyclopedia of Genes and Genomes