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Table 2 Top 20 biological processes by GO BP analysis in 3 cohorts

From: Bioinformatics analysis on multiple Gene Expression Omnibus datasets of the hepatitis B virus infection and its response to the interferon-alpha therapy

Rank

Cohort 1

Cohort 2

Cohort 3

1

immune response

immune response

small molecule metabolic process

2

small molecule metabolic process

small molecule metabolic process

signal transduction

3

inflammatory response

cell adhesion

immune response

4

cell adhesion

inflammatory response

positive regulation of transcription from RNA polymerase II promoter

5

signal transduction

signal transduction

negative regulation of apoptotic process

6

negative regulation of apoptotic process

negative regulation of apoptotic process

transcription, DNA-dependent

7

apoptotic process

negative regulation of transcription, DNA-dependent

innate immune response

8

negative regulation of transcription, DNA-dependent

axon guidance

intracellular protein kinase cascade

9

mitotic cell cycle

protein phosphorylation

virus-host interaction

10

protein phosphorylation

protein complex assembly

apoptotic process

11

protein complex assembly

response to virus

protein phosphorylation

12

response to virus

blood coagulation

blood coagulation

13

axon guidance

response to organic cyclic compound

positive regulation of transcription, DNA-dependent

14

response to organic cyclic compound

mitotic cell cycle

positive regulation of apoptotic process

15

regulation of immune response

regulation of immune response

negative regulation of transcription from RNA polymerase II promoter

16

response to toxic substance

negative regulation of transcription from RNA polymerase II promoter

cell adhesion

17

blood coagulation

chemotaxis

mitotic cell cycle

18

chemotaxis

platelet activation

transmembrane transport

19

negative regulation of transcription from RNA polymerase II promoter

apoptotic process

axon guidance

20

dendritic cell chemotaxis

dendritic cell chemotaxis

positive regulation of cell migration

  1. GO gene ontology, BP biological process