1978–79 | 1994-95 | |||||
---|---|---|---|---|---|---|
Total | HBeAg(-) | HBV-D3 | Total | HBeAg(-) | HBV-D3 | |
Number of patients | 50 | 16 | 25a | 30 | 13 | 13a |
BCP/pre-core mutation pattern (n° of patients): | ||||||
G1764A | 4 | 1 | 3 | |||
G1896A | 3 | 1 | 1 | 2 | 2 | 1 |
T1753C/A, G1896A | 1 | 1 | ||||
A1762T, G1764A | 1 | 1 | ||||
G1896A, G1899A | 1 | 1 | 1 | 1 | ||
T1753C/A, A1762T, G1764A, G1896A | 1 | 1 | 1 | |||
T1753C/A, A1762T, G1764A, G1899A | 1 | 1 | ||||
T1753C/A, A1762T, G1764A, G1896A, G1899A | 2 | 2 | 1 | |||
Patients with at least one BCP/pre-core mutation (n°,%) | 6 (12.0%)# | 2 (12.5%)§ | 2 (8.0%)^ | 12 (40.0%)# | 8 (61.5%)§ | 6 (46.0%)^ |