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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: SPS-neutralization in tissue samples for efficacy testing of antimicrobial peptides

Fig. 4

SPS-neutralization in efficacy tests of SAAP-148 against gram-positive and gram-negative bacteria. Ninety μL of 107 CFU/mL MRSA (LUH14616 and Mu50), E. faecalis (ATCC 29212), P. aeruginosa (PAO1; ATCC BAA47), E. coli (ATCC 35218) and A. baumannii were exposed to 10 μL of 1% (wt/v) SAAP-148 in PBS or PBS for 30 min. Subsequently, samples were homogenized in 500 μL of PBS with or without 0.05% (wt/v) SPS. The means and SD of six independent experiments performed in duplicate are shown. Results are expressed as the number of surviving bacteria in log10 CFU/mL. * indicates significant difference as compared to the samples without SPS (*p < 0.05); **p < 0.01)

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