Table 3 Serum levels of TNF-α, IL-12 and IL-13 in brucellosis patients and control groups with different genotypes

IL-13 (−1512A/C)

0.07

Genotypes

AA

AC

CC

p-value ^a

Case (n = 107)

2.29 ± 2.31

4.87 ± 16.06

2.47 ± 0.60

< 0.001

Control (n = 107)

1.89 ± 1.28

2.41 ± 1.68

1.62 ± 1.14

< 0.001

p-value ^C

0.58

0.16

0.21

IL-13(−1112 C/T)

Genotypes

CC

CT

TT

0.187

Case (n = 107)

2.47 ± 1.62

4.59 ± 16.06

3.29 ± 3.08

< 0.001

Control (n = 107)

1.82 ± 1.27

2.34 ± 1.66

2.21 ± 1.46

< 0.001

p-value ^C

0.24

0.19

0.26

TNF-α (−238 G/A)

0.718

Genotypes

AA

AG

GG

Case (n = 107)

–

15.71 ± 63.22

10.22 ± 16.50

< 0.001

Control (n = 107)

–

1.28 ± 1.39

1.72 ± 1.54

< 0.001

p-value ^C

–

0.02

0.07

IL-12 (+1188 A/C)

0.172

Genotypes

AA

AC

CC

Case (n = 107)

2.71 ± 1.69

4.85 ± 5.47

3.28 ± 1.20

< 0.001

Control (n = 107)

2.60 ± 1.67

2.70 ± 2.10

2.66 ± 2.03

< 0.001

p-value ^C

0.89

0.003

0.02