From: Mutation in MPT64 gene influencing diagnostic accuracy of SD Bioline assay (capilia)
Sample Number | Liquid Culture | ZN Smear | Capilia | MTBDR plus assay | Mutation | Phenotypic effect |
---|---|---|---|---|---|---|
K1 | + | + | – | + | 26th position G deletion | Frameshift from 9th amino acid leading to stop codon after 41st amino acid |
K2 | + | + | – | + | 37th position C deletion | Frameshift from 13th amino acid leading to stop codon after 41st amino acid |
K3 | + | + | – | + | 26th position G deletion | Frameshift from 9th amino acid leading to stop codon after 41st amino acid |
K4 | + | + | – | + | 37th position C deletion | Frameshift from 13th amino acid leading to stop codon after 37th amino acid |
K5 | + | + | – | + | 37th position C deletion | Frameshift from 13th amino acid leading to stop codon after 41st amino acid |
K6 | + | + | – | + | 26th position G deletion | Frameshift from 9th amino acid leading to stop codon after 41st amino acid |
K7 | + | + | – | + | 6th position G insertion | Frameshift from 3rd amino acid leading to stop codon after 88th amino acid |
K8 | + | + | – | + | 37th position C deletion | Frameshift from 13th amino acid leading to stop codon after 41st amino acid |
K9 | + | + | – | + | 26th position G deletion | Frameshift from 9th amino acid leading to stop codon after 41st amino acid |
K10 | + | + | – | + | 6th position G insertion | Frameshift from 3rd amino acid leading to stop codon after 88th amino acid |
K11 (Control) | + | + | + | + | No mutation |