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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy

Fig. 3

Increased circulating levels of AGE and sRAGE in bilateral and cavitary disease and also marker of bacterial burden in TB-DM participants. a The plasma levels of AGE, sRAGE, S100A12 and HMGB-1 were measured in TB-DM individuals with bilateral versus unilateral disease. b The plasma levels of AGE, sRAGE, S100A12 and HMGB-1 were measured in TB-DM individuals with cavitary versus non-cavitary disease. c The relationship between the plasma levels of AGE, sRAGE, S100A12 and HMGB-1 and smear grades as measured by sputum smears was examined in TB-DM individuals. The data are illustrated as scatter plots with each circle representing a single participant. P values were calculated using the Mann-Whitney test with Holm’s correction for multiple comparisons. For bacterial burden correlation, P values were calculated using the Linear trend post-test

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BMC Infectious Diseases

ISSN: 1471-2334

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