Characteristics and outcome of influenza-associated encephalopathy/encephalitis among children in a tertiary pediatric hospital in Italy, 2017–2019

Table 3 Clinical and laboratory difference in age subgroups

	0- ≤ 2 years: 6 (40%)	3–10 years: 9 (60%)	p value
Neurological manifestation
-Altered consciousness	5	4	0.287
-Convulsions	0	6	0.028
Respiratory manifestations	6	5
-Dyspnea	3	1	0.235
Laboratory values
-leukocyte count (/mm³)	8,835	7,290	1.000
-neutrophil count (/mm³)	6,564.5	6,031	0.607
-lymphocyte count (/mm³)	1,928.5	1,093	0.776
-Sodium level (mEq/L)	136	135	0.776
-CRP value at admission (mg/dl)	1.9	2.38	0.088
-Highest CRP value (mg/dl)	2.2	2.46	0.955
Other influenza-related complications
-PICU admission	4	0	0.011

Legend: We analyzed difference in two age subgroups: 0–2 years, comprising 6 patients (40% of the sample) and 3–10 years, comprising 9 patients (60% of the sample). For each neurological manifestation, respiratory manifestation and other influenza-related complication, we reported the number of patients in the subgroups presenting the feature and searched for a statistically significant difference (p < 0.05). For each laboratory value, we reported median values in the subgroups and searched for a statistically significant difference(p < 0.05)

ISSN: 1471-2334