Table 1 Demographic and clinical characteristic of patients
Age (month) [median (IQR)]: 27 (7–48) | |
0- ≤ 2 years [n (%)]: | 6 (40%) |
2–10 years [n (%)]: | 9 (60%) |
Sex | |
Male [n (%)]: | 4 (26.7%) |
Female [n (%)]: | 11 (73.3%) |
Comorbid disease [n (%)]: | 5 (33.3%) |
Chronic neurological diseases: [n (%)]: | 4 (26.7%) |
Congenital heart disease [n (%)]: | 1 (6.7%) |
Seasonal influenza vaccination: | none |
Time between flu-like symptoms and neurological manifestations | |
[median (IQR)]: | 1 day (0 h-3 days) |
Unit or department of admission [n (%)] | |
Pediatric department: | 14 (93.3%) |
Pediatric intensive care unit: | 1 (6.7%) |
Duration of hospitalization | |
[median (IQR)]: | 9 days (7–12 days) |
Clinical presentation at admission [n (%)] | |
Fever: | 13 (86.7%) |
• Maximum [median (IQR)] | 38.7 (37.6–39.2) °C |
Neurologic manifestations: | 15 (100%) |
• Seizures: | 6 (40%) |
• Altered consciousness: | 8 (53.3%) |
• Ataxia: | 1 (6.7%) |
Respiratory manifestations: | 11 (73.3%) |
• Cough: | 7 (46.7%) |
• Dyspnea | 4 (26.7%) |
Other influenza-related complications [n (%)] | |
Respiratory failure: | 4 (26.7%) |
Liver impairment: | 1 (6.7%) |
PICU admission: | 4 (26.7%) |
Days in PICU [median (IQR)]: | 5.5 (4.25–15) |