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Table 1 Demographic and clinical characteristic of patients

From: Characteristics and outcome of influenza-associated encephalopathy/encephalitis among children in a tertiary pediatric hospital in Italy, 2017–2019

Age (month) [median (IQR)]: 27 (7–48)
 0- ≤ 2 years [n (%)]:6 (40%)
 2–10 years [n (%)]:9 (60%)
Sex
 Male [n (%)]:4 (26.7%)
 Female [n (%)]:11 (73.3%)
Comorbid disease [n (%)]:5 (33.3%)
 Chronic neurological diseases: [n (%)]:4 (26.7%)
 Congenital heart disease [n (%)]:1 (6.7%)
Seasonal influenza vaccination:none
Time between flu-like symptoms and neurological manifestations
  [median (IQR)]:1 day (0 h-3 days)
Unit or department of admission [n (%)]
 Pediatric department:14 (93.3%)
 Pediatric intensive care unit:1 (6.7%)
Duration of hospitalization
  [median (IQR)]:9 days (7–12 days)
Clinical presentation at admission [n (%)]
 Fever:13 (86.7%)
  • Maximum [median (IQR)]38.7 (37.6–39.2) °C
 Neurologic manifestations:15 (100%)
  • Seizures:6 (40%)
  • Altered consciousness:8 (53.3%)
  • Ataxia:1 (6.7%)
 Respiratory manifestations:11 (73.3%)
  • Cough:7 (46.7%)
  • Dyspnea4 (26.7%)
Other influenza-related complications [n (%)]
 Respiratory failure:4 (26.7%)
 Liver impairment:1 (6.7%)
 PICU admission:4 (26.7%)
 Days in PICU [median (IQR)]:5.5 (4.25–15)