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Table 1 Literature review of melioidosis thrombosis cases with summary of predisposing factors, clinical presentation, treatment and outcome

From: Fatal deep venous thrombosis and pulmonary embolism secondary to melioidosis in China: case report and literature review

Reference2006 [10]2007 [16]2018 [17]2010 [18]2015 [19]2017 [11]Our data
Cases number1111111
Country/AreaThailandMalaysiaIndiaBruneiFranceThailandChina
Age(y)/Gende42/male33/male23/male48/male52/male54/male54/male
Underlying diseasediabetes, mild alcoholic cirrhosisNANAdiabetesNAdiabetesdiabetes
Presentationfever, headache, left hemiparesis, focal seizure, increased intracranial pressurefever, seizures, altered conscious level and neck stiffness,diplopia, decreased hearingfever, rigor, abdominal pain, loss of appetite, weight lossfever with chills, palpitations and an unproductive cough.febrile, icteric, dehydratedfebrile, painful in left thigh with left lower limb swelling, chest tightness, shortness of breath
Thrombus sitedural sinussuperior sagittal sinusdural venous sinussplenic veinsplenic vein, right portion of the portal veinleft portal veinleft lower extremity
Sources Identificationbloodbloodbrain tissue biopsyblood, pancreas, lung, spleen, liverblood, sputumbloodblood, sputum, bone marrow
Antibiotic therapyceftazidimeNAceftazidime, cotrimoxazoleceftazidime, amoxicillin-clavulanic acid, doxycycline, co-trimoxazoleceftazidime, meropenem, co-trimoxazole, amoxicillin-clavulanic acid,ceftazidime, amoxicillin-clavulanic acidlevofloxacin, cefoperazone/tazobactam, imipenem
Other therapyantiepileptic drug and anticoagulantcraniectomy and drainage of the abscessanticoagulantno other therapyanticoagulantanticoagulantanticoagulant (low molecular heparin)
Outcomerecoveredrecoveredno improvementrecoveredrecoveredrecovereddied
  1. *NA Not available