Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission

Table 1 Characteristics of the mother and children in Family 1 and Family 2

Family	Patients	Year of birth	Immuno- prophylaxis	Gender	Serum ALT level	HBV serological status in 2016				Quantification of HBV DNA
Family	Patients	Year of birth	Immuno- prophylaxis	Gender	Serum ALT level	HBsAg	HBeAg	Anti-HBs	Anti-HBc	Sample	Year of sampling	HBV DNA (log copies/mL)
1	Mother	1985	Not done	Female	17	Pos	Pos	Neg	Pos	serum	2016	9.0
	1st-born child	2004	Failure	Female	22	Pos	Pos	Neg	Pos	Dried umbilical cord	2004	3.7
	1st-born child	2004	Failure	Female	22	Pos	Pos	Neg	Pos	serum	2016	7.8
	2nd-born child	2007	Failure	Male	12	Pos	Pos	Neg	Pos	Dried umbilical cord	2007	4.7
	2nd-born child	2007	Failure	Male	12	Pos	Pos	Neg	Pos	serum	2016	8.3
	3rd-born child	2015	Success	Female	11	Neg	Neg	Pos	Neg	Dried umbilical cord	2015	3.8
2	Mother	1988	Not done	Female	28	Pos	Pos	Neg	Pos	Nail	2016	3.8
	1st-born child	2013	Failure	Female	134	Pos	Pos	Neg	Pos	Dried umbilical cord	2013	4.5
										serum	2016	8.6
										Nail	2016	4.9
	2nd-bornchild	2014	Failure	Male	129	Pos	Pos	Neg	Pos	Dried umbilical cord	2014	3.8
										serum	2016	7.6
										Nail	2016	3.8

ISSN: 1471-2334