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Table 1 Characteristics of the mother and children in Family 1 and Family 2

From: Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission

FamilyPatientsYear of birthImmuno- prophylaxisGenderSerum ALT
level
HBV serological status in 2016Quantification of HBV DNA
HBsAgHBeAgAnti-HBsAnti-HBcSampleYear of samplingHBV DNA (log copies/mL)
1Mother1985Not doneFemale17PosPosNegPosserum20169.0
1st-born child2004FailureFemale22PosPosNegPosDried umbilical cord20043.7
serum20167.8
2nd-born child2007FailureMale12PosPosNegPosDried umbilical cord20074.7
serum20168.3
3rd-born child2015SuccessFemale11NegNegPosNegDried umbilical cord20153.8
2Mother1988Not doneFemale28PosPosNegPosNail20163.8
1st-born child2013FailureFemale134PosPosNegPosDried umbilical cord20134.5
serum20168.6
Nail20164.9
2nd-bornchild2014FailureMale129PosPosNegPosDried umbilical cord20143.8
serum20167.6
Nail20163.8
  1. Pos: positive Neg: negative