Skip to main content

Advertisement

Table 3 Flow cytometry-based detection (MFI) of flavivirus envelope protein in subpopulations of human peripheral blood mononuclear cells after ex-vivo infectiona

From: Zika virus infects human blood mononuclear cells

DonorsPBMC subpopulations (MFI)
CD3+CD4+4G2+CD3+CD8+4G2+CD3CD19+4G2+CD14+4G2+
D1201.0194.00189.0266.0
D3142.0135.00167.0zero
D42.0zero374.0NDb
D527.012.0042.0NDb
D719.0zerozerozero
D9zerozerozero123.0
D14zerozerozero6.0
D15zerozero27.0zero
D16zero44.00zerozero
  1. aMFI (Median of fluorescence intensity) was calculated by subtracting the median of 4G2 labeling in PBMCs subpopulations who received ZIKV as compared with the background 4G2 labeling profile in PBMCs subpopulations from the same donor, but that were not exposed to ZIKV (MOCK). Donors D2, D6, D8, D10, D11, D12 and D13 cells were all negative for 4G2 staining. bND = not determined, as very low amounts of these subpopulations were detected