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Table 5 Discriminating performance of the combined marker (IL-6 + PTX3), IL-6, and PTX3 for septic shock

From: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

BiomarkersAUC (95% CI)pCut-offSensitivity (%)Specificity (%)
IL-6 + PTX30.806 (0.719–0.894)< 0.00152.0 (score)82.771.1
IL-60.795 (0.702–0.883)< 0.001348.92 (pg/mL)76.178.4
PTX30.703 (0.603–0.812)0.00158.28 (ng/mL)56.576.5
  1. AUC area under the curve, CI confidence interval, IL-6 interleukin-6, PTX3 pentraxin 3