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Table 3 Diagnostic Value of Interleukin-6 and Pentraxin 3 for Patients with Sepsis and Septic Shock

From: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

BiomarkerSeverityAUC (95% CI)Cut-off valueSensitivity (%)Specificity (%)P value
IL-6Sepsis0.89 (0.83–0.94)52.6080.488.9< 0.001
(pg/mL)Septic shock0.80 (0.71–0.89)348.9276.178.4< 0.001
PTX3Sepsis0.84 (0.78–0.91)15.1076.380.0< 0.001
(ng/mL)Septic shock0.70 (0.60–0.81)58.2856.576.50.001
  1. AUC area under the curve, CI confidence interval, IL-6 interleukin-6, PTX3 pentraxin 3