Biomarker | Severity | AUC (95% CI) | Cut-off value | Sensitivity (%) | Specificity (%) | P value |
---|---|---|---|---|---|---|
IL-6 | Sepsis | 0.89 (0.83–0.94) | 52.60 | 80.4 | 88.9 | < 0.001 |
(pg/mL) | Septic shock | 0.80 (0.71–0.89) | 348.92 | 76.1 | 78.4 | < 0.001 |
PTX3 | Sepsis | 0.84 (0.78–0.91) | 15.10 | 76.3 | 80.0 | < 0.001 |
(ng/mL) | Septic shock | 0.70 (0.60–0.81) | 58.28 | 56.5 | 76.5 | 0.001 |