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Table 3 Diagnostic Value of Interleukin-6 and Pentraxin 3 for Patients with Sepsis and Septic Shock

From: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

Biomarker

Severity

AUC (95% CI)

Cut-off value

Sensitivity (%)

Specificity (%)

P value

IL-6

Sepsis

0.89 (0.83–0.94)

52.60

80.4

88.9

< 0.001

(pg/mL)

Septic shock

0.80 (0.71–0.89)

348.92

76.1

78.4

< 0.001

PTX3

Sepsis

0.84 (0.78–0.91)

15.10

76.3

80.0

< 0.001

(ng/mL)

Septic shock

0.70 (0.60–0.81)

58.28

56.5

76.5

0.001

  1. AUC area under the curve, CI confidence interval, IL-6 interleukin-6, PTX3 pentraxin 3