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Table 1 Baseline Characteristics of the Study Population

From: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

VariableTotal patients (n = 97)Sepsis (n = 51)Septic shock (n = 46)Controls(n = 45)
Age, median (range)75 (42–98)76 (42–98)74 (42–96)68 (37–81)
Sex, n (%)
 Male54 (56)28 (55)26 (57)25 (56)
 Female43 (44)23 (45)20 (43)20 (44)
Infection site, n (%)
 Respiratory63 (64.9)33 (64.7)30 (65.2)
 Genitourinary32 (33.0)19 (37.3)13 (28.3)
 Cardiovascular3 (3.1)0 (0.0)3 (6.5)
 Gastrointestinal2 (2.1)0 (0.0)2 (4.3)
 Musculoskeletal2 (2.1)1 (2.0)1 (2.2)
 Central nervous1 (1.0)0 (0.0)1 (2.2)
 Hepatobiliary1 (1.0)0 (0.0)1 (2.2)
 Skin and soft tissue1 (1.0)1 (2.0)0 (0.0)
 Unknown5 (5.2)2 (3.9)3 (6.5)
Underlying disease
 Coronary artery disease11 (11.3)5 (9.8)6 (13.0)
 Malignancy10 (10.3)4 (7.8)6 (13.0)
 Rheumatic disease4 (4.1)2 (3.9)2 (4.3)
SOFA score, median (IQR)8 (4–11)6 (3–9)10 (6–13)
APACHE II score, median (IQR)21 (13–30)18 (10–27)25 (16–35)
Laboratory value,median (IQR) or mean ± SEM
 Procalcitonin (ng/mL)1.6 (0.5–10.7)0.3 (0.2–1.2)3.4 (1.6–20.3) 
 CRP (mg/dL)10 (6–20)10 (5–20)11 (7–21) 
 Lactate (mmol/L)3.6 (2.6–4.6)1.9 (1.1–2.8)5.5 (3.6–7.5) 
 Creatinine (mg/dL)2.5 ± 0.22.1 ± 0.22.9 ± 0.2 
 Bilirubin (mg/dL)2.2 ± 0.41.7 ± 0.32.8 ± 0.5 
 Platelet (× 1000/μL)203 ± 12.4251 ± 14.3153 ± 10.6 
Positive blood cultures, n (%)75 (77.3)35 (68.6)40 (87.0)
ICU days, median (IQR)9 (5–14)8 (4–11)11 (7–16)
Length of stay, median (IQR)13 (8–18)11 (7–16)15 (9–19)
  1. SOFA sequential organ-failure assessment, IQR interquartile range, APACHE acute physiology and chronic health evaluation, CRP C-reactive protein, SEM standard error of the mean, ICU intensive care unit