BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy

Table 1 Management and outcome of 12 kidney transplant recipients with BK polyomavirus-associated nephropathy

No.	Diagnosis of BKPyVAN	Adjustment of immunosuppression			Adjunctive therapies			BKPyV clearance	Allograft dysfunction
No.	Diagnosis of BKPyVAN	Mycophenolic acid	Tacrolimus C₀ level of 3–5 ng/mL	Switched tacrolimus to cyclosporine	Cidofovir	IVIG	Leflunomide	BKPyV clearance	Allograft dysfunction
1	Presumptive	Discontinuation	Yes	No	Yes	No	Yes	Yes	Yes
2	Proven	Discontinuation	Yes	Yes	No	Yes	Yes	No	Yes
3	Presumptive	Reduction	Yes	Yes	Yes	Yes	Yes	Yes	No
4	Presumptive	Discontinuation	Yes	No	Yes	No	Yes	No	Yes
5	Proven	Discontinuation	Yes	No	Yes	No	No	No	Yes
6	Possible	Reduction	Yes	No	No	No	No	Yes	No
7	Proven	Discontinuation	Yes	Yes	Yes	Yes	Yes	No	Yes
8	Presumptive	Reduction	Yes	No	No	No	Yes	Yes	Yes
9	Proven	Discontinuation	Yes	Yes	No	Yes	Yes	No	Yes
10	Proven	Discontinuation	Yes	No	No	No	Yes	No	Yes
11	Proven	Discontinuation	Yes	Yes (sirolimus)	Yes	No	Yes	No	No
12	Proven	Discontinuation	Yes	No	No	No	No	No	No

BKPyV BK polyomavirus, BKPyVAN BK polyomavirus-associated nephropathy, IVIG intravenous immunoglobulin

ISSN: 1471-2334