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Table 1 Management and outcome of 12 kidney transplant recipients with BK polyomavirus-associated nephropathy

From: BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy

No.Diagnosis of BKPyVANAdjustment of immunosuppressionAdjunctive therapiesBKPyV clearanceAllograft dysfunction
Mycophenolic acidTacrolimus C0 level of 3–5 ng/mLSwitched tacrolimus to cyclosporineCidofovirIVIGLeflunomide
1PresumptiveDiscontinuationYesNoYesNoYesYesYes
2ProvenDiscontinuationYesYesNoYesYesNoYes
3PresumptiveReductionYesYesYesYesYesYesNo
4PresumptiveDiscontinuationYesNoYesNoYesNoYes
5ProvenDiscontinuationYesNoYesNoNoNoYes
6PossibleReductionYesNoNoNoNoYesNo
7ProvenDiscontinuationYesYesYesYesYesNoYes
8PresumptiveReductionYesNoNoNoYesYesYes
9ProvenDiscontinuationYesYesNoYesYesNoYes
10ProvenDiscontinuationYesNoNoNoYesNoYes
11ProvenDiscontinuationYesYes (sirolimus)YesNoYesNoNo
12ProvenDiscontinuationYesNoNoNoNoNoNo
  1. BKPyV BK polyomavirus, BKPyVAN BK polyomavirus-associated nephropathy, IVIG intravenous immunoglobulin