Variable | Total | Early-period Group | Later-period Group | OR | 95% CI | P | |
---|---|---|---|---|---|---|---|
N = 313 | N = 97 | N = 216 | Lower | Upper | |||
Manifestations | |||||||
 Fever | 262 (83.7) | 81 (83.5 ) | 181(83.8) | 1.022 | 0.535 | 1.951 | 0.949 |
 Cardiac murmurs | 262 (83.7) | 87 (89.7) | 175(81.0) | 0.491 | 0.235 | 1.026 | 0.055 |
 Splenomegaly | 72 (23.0) | 15 (15.5) | 57 (26.4) | 1.960 | 1.046 | 3.673 | 0.034 |
 Chest pain | 38 (12.1) | 14 (14.4) | 24(11.1) | 0.741 | 0.365 | 1.504 | 0.405 |
 Janeway lesion | 11 (3.5) | 6 (6.2 ) | 5 (2.3) | 0.359 | 0.107 | 1.208 | 0.165 |
 Osler nodes | 5 (1.6 ) | 3 (3.1) | 2 (0.9) | 0.293 | 0.048 | 1.781 | 0.354 |
Labotory foundings | |||||||
 Leukocytosis or neutrophilia | 199 (63.6) | 64 (66.0) | 135 (62.5) | 0.859 | 0.520 | 1.420 | 0.554 |
 Anemia | 247 (78.9) | 80 (82.5) | 167 (77.3) | 0.724 | 0.392 | 1.336 | 0.301 |
 Hypoproteinemia | 293 (93.6) | 90 (92.8) | 203 (94.0 ) | 1.215 | 0.469 | 3.146 | 0.689 |
Comlications | |||||||
 Heart insufficiency | 182 (58.1) | 60 (61.9) | 122 (56.5) | 0.800 | 0.490 | 1.307 | 0.343 |
 Acute congestive heart failure | 67 (21.4) | 23 (23.7) | 44 (20.4) | 0.823 | 0.464 | 1.460 | 0.505 |
Embolism | 82 (26.2) | 19 (19.6) | 63 ( 29.2 ) | 1.690 | 0.946 | 3.022 | 0.075 |
 Ischemic stroke | 69 ( 22.0 ) | 10 ( 10.3 ) | 59 ( 27.3 ) | 3.269 | 1.592 | 6.714 | <0.001 |
 Pulmonary embolism | 11 ( 3.5 ) | 7 ( 7.2 ) | 4 ( 1.9 ) | 0.243 | 0.069 | 0.849 | 0.040 |
 Renal infarction | 7 (2.2) | 3 (3.1) | 4 (1.9) | 0.591 | 0.130 | 2.694 | 0.785 |
 Splenic infarction | 20 (6.4) | 4 (4.1) | 16 (7.4) | 1.860 | 0.605 | 5.717 | 0.272 |
 Hemorrhagic stroke | 27 (8.6) | 7 (7.2) | 20 (9.3) | 1.312 | 0.535 | 3.215 | 0.552 |
 Metastatic abscess | 18 (5.8) | 6 (6.2) | 12 ( 5.6 ) | 0.897 | 0.326 | 2.463 | 0.832 |
 Pulmonary abscess | 14 ( 4.5 ) | 4 ( 4.1 ) | 10 ( 4.6 ) | 1.129 | 0.345 | 3.692 | 0.924 |
 Cerebral abscess | 7 ( 2.2 ) | 3 ( 3.1 ) | 4 ( 1.9 ) | 0.591 | 0.130 | 2.694 | 0.785 |
 Renal insufficiency | 28 ( 8.9 ) | 15 ( 15.5 ) | 13 ( 6.0 ) | 0.350 | 0.160 | 0.768 | 0.007 |
 No complications | 27 ( 8.6 ) | 9 ( 9.3 ) | 18 ( 8.3 ) | 0.889 | 0.384 | 2.056 | 0.783 |