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Table 2 Manifestations and complications of 313 patients

From: A changing profile of infective endocarditis at a tertiary hospital in China: a retrospective study from 2001 to 2018

Variable

Total

Early-period Group

Later-period Group

OR

95% CI

P

N = 313

N = 97

N = 216

Lower

Upper

Manifestations

 Fever

262 (83.7)

81 (83.5 )

181(83.8)

1.022

0.535

1.951

0.949

 Cardiac murmurs

262 (83.7)

87 (89.7)

175(81.0)

0.491

0.235

1.026

0.055

 Splenomegaly

72 (23.0)

15 (15.5)

57 (26.4)

1.960

1.046

3.673

0.034

 Chest pain

38 (12.1)

14 (14.4)

24(11.1)

0.741

0.365

1.504

0.405

 Janeway lesion

11 (3.5)

6 (6.2 )

5 (2.3)

0.359

0.107

1.208

0.165

 Osler nodes

5 (1.6 )

3 (3.1)

2 (0.9)

0.293

0.048

1.781

0.354

Labotory foundings

 Leukocytosis or neutrophilia

199 (63.6)

64 (66.0)

135 (62.5)

0.859

0.520

1.420

0.554

 Anemia

247 (78.9)

80 (82.5)

167 (77.3)

0.724

0.392

1.336

0.301

 Hypoproteinemia

293 (93.6)

90 (92.8)

203 (94.0 )

1.215

0.469

3.146

0.689

Comlications

 Heart insufficiency

182 (58.1)

60 (61.9)

122 (56.5)

0.800

0.490

1.307

0.343

 Acute congestive heart failure

67 (21.4)

23 (23.7)

44 (20.4)

0.823

0.464

1.460

0.505

Embolism

82 (26.2)

19 (19.6)

63 ( 29.2 )

1.690

0.946

3.022

0.075

 Ischemic stroke

69 ( 22.0 )

10 ( 10.3 )

59 ( 27.3 )

3.269

1.592

6.714

<0.001

 Pulmonary embolism

11 ( 3.5 )

7 ( 7.2 )

4 ( 1.9 )

0.243

0.069

0.849

0.040

 Renal infarction

7 (2.2)

3 (3.1)

4 (1.9)

0.591

0.130

2.694

0.785

 Splenic infarction

20 (6.4)

4 (4.1)

16 (7.4)

1.860

0.605

5.717

0.272

 Hemorrhagic stroke

27 (8.6)

7 (7.2)

20 (9.3)

1.312

0.535

3.215

0.552

 Metastatic abscess

18 (5.8)

6 (6.2)

12 ( 5.6 )

0.897

0.326

2.463

0.832

 Pulmonary abscess

14 ( 4.5 )

4 ( 4.1 )

10 ( 4.6 )

1.129

0.345

3.692

0.924

 Cerebral abscess

7 ( 2.2 )

3 ( 3.1 )

4 ( 1.9 )

0.591

0.130

2.694

0.785

 Renal insufficiency

28 ( 8.9 )

15 ( 15.5 )

13 ( 6.0 )

0.350

0.160

0.768

0.007

 No complications

27 ( 8.6 )

9 ( 9.3 )

18 ( 8.3 )

0.889

0.384

2.056

0.783

  1. Variables are presented as count (%). P value were estimated by Chi-squared tests. One patient could have two or more manifestations and complications