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Table 2 Manifestations and complications of 313 patients

From: A changing profile of infective endocarditis at a tertiary hospital in China: a retrospective study from 2001 to 2018

VariableTotalEarly-period GroupLater-period GroupOR95% CIP
N = 313N = 97N = 216LowerUpper
Manifestations
 Fever262 (83.7)81 (83.5 )181(83.8)1.0220.5351.9510.949
 Cardiac murmurs262 (83.7)87 (89.7)175(81.0)0.4910.2351.0260.055
 Splenomegaly72 (23.0)15 (15.5)57 (26.4)1.9601.0463.6730.034
 Chest pain38 (12.1)14 (14.4)24(11.1)0.7410.3651.5040.405
 Janeway lesion11 (3.5)6 (6.2 )5 (2.3)0.3590.1071.2080.165
 Osler nodes5 (1.6 )3 (3.1)2 (0.9)0.2930.0481.7810.354
Labotory foundings
 Leukocytosis or neutrophilia199 (63.6)64 (66.0)135 (62.5)0.8590.5201.4200.554
 Anemia247 (78.9)80 (82.5)167 (77.3)0.7240.3921.3360.301
 Hypoproteinemia293 (93.6)90 (92.8)203 (94.0 )1.2150.4693.1460.689
Comlications
 Heart insufficiency182 (58.1)60 (61.9)122 (56.5)0.8000.4901.3070.343
 Acute congestive heart failure67 (21.4)23 (23.7)44 (20.4)0.8230.4641.4600.505
Embolism82 (26.2)19 (19.6)63 ( 29.2 )1.6900.9463.0220.075
 Ischemic stroke69 ( 22.0 )10 ( 10.3 )59 ( 27.3 )3.2691.5926.714<0.001
 Pulmonary embolism11 ( 3.5 )7 ( 7.2 )4 ( 1.9 )0.2430.0690.8490.040
 Renal infarction7 (2.2)3 (3.1)4 (1.9)0.5910.1302.6940.785
 Splenic infarction20 (6.4)4 (4.1)16 (7.4)1.8600.6055.7170.272
 Hemorrhagic stroke27 (8.6)7 (7.2)20 (9.3)1.3120.5353.2150.552
 Metastatic abscess18 (5.8)6 (6.2)12 ( 5.6 )0.8970.3262.4630.832
 Pulmonary abscess14 ( 4.5 )4 ( 4.1 )10 ( 4.6 )1.1290.3453.6920.924
 Cerebral abscess7 ( 2.2 )3 ( 3.1 )4 ( 1.9 )0.5910.1302.6940.785
 Renal insufficiency28 ( 8.9 )15 ( 15.5 )13 ( 6.0 )0.3500.1600.7680.007
 No complications27 ( 8.6 )9 ( 9.3 )18 ( 8.3 )0.8890.3842.0560.783
  1. Variables are presented as count (%). P value were estimated by Chi-squared tests. One patient could have two or more manifestations and complications