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Table 4 Risk factors for hospital mortality

From: Intra-abdominal infections: the role of different classifications on the selection of the best antibiotic treatment

 TotalHospital mortalityp valueCrude OR
Age ≥ 70, n (%)101 (66)27 (27)0.0552.398
Male gender, n (%)74 (48)13 (18)0.1940.599
Karnofsky Performance Status Scale < 70, n (%)112 (73)20 (18)0.0420.435
Diabetes, n (%)45 (29)10 (22)0.9780.988
Liver disease, n (%)14 (9)4 (29)0.512a1.467
Solid tumour, n (%)45 (29)14 (31)0.0822.010
AIDS, n (%)1 (1)0 (0)1.000a
Chronic kidney disease, n (%)26 (17)10 (39)0.0272.708
Congestive heart failure, n (%)11 (7)0 (0)0.124a
Myocardial infarction, n (%)10 (7)1 (10)0.461a0.374
Chronic obstructive pulmonary disease, n (%)10 (7)3 (30)0.693a1.562
Peripheral vascular disease, n (%)22 (14)4 (18)0.785a0.756
Cerebrovascular accident/transient ischemic attack, n (%)14 (9)0 (0)0.041a
Dementia, n (%)11 (7)5 (46)0.066a3.276
Hemiplegia, n (%)1 (1)0 (0)1.000a
Connective tissue disease, n (%)2 (1)1 (50)0.394a3.606
Leukemia, n (%)3 (2)2 (67)0.123a7.437
Malignant lymphoma, n (%)1 (0,6)0 (0)1.000a
Peptic ulcer disease, n (%)4 (3)0 (0)0.576a
Total Score - Charlson Comorbidity Index, mean ± SD5 ± 35 ± 30.0450.866 per point
Residence in a long-term care facility or nursing home, n (%)7 (5)2 (29)0.469a1.484
Previous colonization/infection by DR pathogen, n (%)29 (19)4 (14)0.322a0.507
Previous antibiotic therapy, n (%)39 (25)11 (28)0.2861.571
Previous hospitalization, n (%)82 (53)19 (23)0.7271.146
Previous invasive procedures, n (%)78 (51)18 (23)0.6441.200
Initial antibiotic therapy adequate, n (%)98 (64)21 (21)0.7970.902
Polymicrobial flora, n (%)59 (38)18 (31)0.0492.168
Sensitive to ATB I, n (%)80 (52)12 (15)0.0300.417
Sensitive to ATB 2, n (%)105 (68)19 (18)0.0840.501
Positive blood cultures, n (%)69 (57)16 (15)0.0650.429
Post-operative infection, n (%)19 (12)3 (16)0.570a1.590
Place of acquisition – classification, n (%)154 (100)34 (22)0.790
Community-acquired, n (%)83 (54)18 (22)1.000
Healthcare-associated, n (%)45 (29)9 (20)1.330
Hospital-acquired, n (%)26 (17)7 (27)1.474
Extent of infection – classification, n (%)154 (100)34 (22)0.195a
Uncomplicated, n (%)25 (16)3 (12)1.000
Complicated, n (%)129 (84)31 (24)2.320
  1. aFisher’s exact test; AIDS acquired immune deficiency syndrome, DR drug-resistant, OR odds ratio, ATB I non-pseudomonal cephalosporin or ciprofloxacin plus metronidazole, ATB 2 piperacillin/tazobactam