Table 4 Risk factors for hospital mortality

Age ≥ 70, n (%)

101 (66)

27 (27)

0.055

2.398

Male gender, n (%)

74 (48)

13 (18)

0.194

0.599

Karnofsky Performance Status Scale < 70, n (%)

112 (73)

20 (18)

0.042

0.435

Diabetes, n (%)

45 (29)

10 (22)

0.978

0.988

Liver disease, n (%)

14 (9)

4 (29)

0.512^a

1.467

Solid tumour, n (%)

45 (29)

14 (31)

0.082

2.010

AIDS, n (%)

1 (1)

0 (0)

1.000^a

–

Chronic kidney disease, n (%)

26 (17)

10 (39)

0.027

2.708

Congestive heart failure, n (%)

11 (7)

0 (0)

0.124^a

–

Myocardial infarction, n (%)

10 (7)

1 (10)

0.461^a

0.374

Chronic obstructive pulmonary disease, n (%)

10 (7)

3 (30)

0.693^a

1.562

Peripheral vascular disease, n (%)

22 (14)

4 (18)

0.785^a

0.756

Cerebrovascular accident/transient ischemic attack, n (%)

14 (9)

0 (0)

0.041^a

–

Dementia, n (%)

11 (7)

5 (46)

0.066^a

3.276

Hemiplegia, n (%)

1 (1)

0 (0)

1.000^a

–

Connective tissue disease, n (%)

2 (1)

1 (50)

0.394^a

3.606

Leukemia, n (%)

3 (2)

2 (67)

0.123^a

7.437

Malignant lymphoma, n (%)

1 (0,6)

0 (0)

1.000^a

–

Peptic ulcer disease, n (%)

4 (3)

0 (0)

0.576^a

–

Total Score - Charlson Comorbidity Index, mean ± SD

5 ± 3

5 ± 3

0.045

0.866 per point

Residence in a long-term care facility or nursing home, n (%)

7 (5)

2 (29)

0.469^a

1.484

Previous colonization/infection by DR pathogen, n (%)

29 (19)

4 (14)

0.322^a

0.507

Previous antibiotic therapy, n (%)

39 (25)

11 (28)

0.286

1.571

Previous hospitalization, n (%)

82 (53)

19 (23)

0.727

1.146

Previous invasive procedures, n (%)

78 (51)

18 (23)

0.644

1.200

Initial antibiotic therapy adequate, n (%)

98 (64)

21 (21)

0.797

0.902

Polymicrobial flora, n (%)

59 (38)

18 (31)

0.049

2.168

Sensitive to ATB I, n (%)

80 (52)

12 (15)

0.030

0.417

Sensitive to ATB 2, n (%)

105 (68)

19 (18)

0.084

0.501

Positive blood cultures, n (%)

69 (57)

16 (15)

0.065

0.429

Post-operative infection, n (%)

19 (12)

3 (16)

0.570^a

1.590

Place of acquisition – classification, n (%)

154 (100)

34 (22)

0.790

–

Community-acquired, n (%)

83 (54)

18 (22)

–

1.000

Healthcare-associated, n (%)

45 (29)

9 (20)

–

1.330

Hospital-acquired, n (%)

26 (17)

7 (27)

–

1.474

Extent of infection – classification, n (%)

154 (100)

34 (22)

0.195^a

–

Uncomplicated, n (%)

25 (16)

3 (12)

–

1.000

Complicated, n (%)

129 (84)

31 (24)

–

2.320