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Table 1 Population’s general characteristics and risk factors for IAI by pathogens sensitive to ATB 1 or to ATB 2

From: Intra-abdominal infections: the role of different classifications on the selection of the best antibiotic treatment

 

Total

IAI by pathogens susceptible to ATB 1

p value

IAI by pathogens susceptible to ATB 2

p value

Age ≥ 70, n (%)

101 (66)

52 (65)

0.874

72 (64)

0.253

Male gender, n (%)

74 (48)

46 (58)

0.015

49 (47)

0.614

Karnofsky Performance Status Scale < 70, n (%)

112 (73)

62 (78)

0.167

73 (70)

0.191

Diabetes, n (%)

45 (29)

19 (24)

0.121

28 (27)

0.308

Liver disease, n (%)

14 (9)

6 (8)

0.475

6 (6)

0.033

Solid tumour, n (%)

45 (29)

23 (29)

0.894

31 (30)

0.904

AIDS, n (%)

1 (1)

1 (1)

1.000a

1 (1)

1.000a

Chronic kidney disease, n (%)

26 (17)

9 (11)

0.052

18 (17)

0.900

Congestive heart failure, n (%)

11 (7)

7 (9)

0.537a

8 (8)

1.000a

Myocardial infarction, n (%)

10 (7)

7 (9)

0.331a

9 (9)

0.171a

Chronic obstructive pulmonary disease, n (%)

10 (7)

6 (8)

0.748a

8 (8)

0.504a

Peripheral vascular disease, n (%)

22 (14)

11 (14)

0.843

14 (13)

0.621

Cerebrovascular accident/transient ischemic attack, n (%)

14 (9)

8 (10)

0.683

11 (11)

0.550a

Dementia, n (%)

11 (7)

3 (4)

0.120a

7 (7)

1.000a

Hemiplegia, n (%)

1 (1)

1 (1)

1.000a

1 (1)

1.000a

Connective tissue disease, n (%)

2 (1)

1 (1)

1.000a

1 (1)

1.000a

Leukemia, n (%)

3 (2)

1 (1)

0.608a

2 (2)

1.000a

Malignant lymphoma, n (%)

1 (1)

1 (1)

1.000a

1 (1)

1.000a

Peptic ulcer disease, n (%)

4 (3)

3 (4)

0.621a

3 (3)

1.000a

Total score - Charlson Comorbidity Index, mean ± SD

5 ± 3

5 ± 3

0.744

5 ± 3

0.352

Residence in a long-term care facility or nursing home, n (%)

7 (5)

2 (3)

0.259a

4 (4)

0.681a

Previous colonization/infection by DR pathogen, n (%)

29 (19)

16 (20)

0.700

20 (19)

0.920

Previous antibiotic therapy, n (%)

39 (25)

14 (18)

0.020

22 (21)

0.068

Previous hospitalization, n (%)

82 (53)

37 (46)

0.070

51 (49)

0.089

Previous invasive procedures, n (%)

78 (51)

34 (43)

0.028

48 (46)

0.082

Post-operative Infection, n (%)

19 (12)

9 (11)

0.670

9 (9)

0.037

  1. aFisher’s exact test; AIDS, acquired immune deficiency syndrome; ATB 1, non-pseudomonal cephalosporin or ciprofloxacin plus metronidazole; ATB 2, piperacillin/tazobactam; DR drug-resistant, OR odds ratio, SD standard deviation