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Table 3 Factors associated with 30-day mortality by univariate analysis in patients with IC

From: Surveillance study of the prevalence, species distribution, antifungal susceptibility, risk factors and mortality of invasive candidiasis in a tertiary teaching hospital in Southwest China

Variable30-day outcomeP-value
Survived (n = 213)Died (n = 30)
Age,years (range)57.8(17–91)62.7(29–81)0.127
Gender (male:female)124:8915:150.394
Underlying comorbidities (n, %)
 Gastrointestinal perforation39 (18.3)9 (30.0)0.132
 Respiratory dysfunction31 (14.6)20 (66.7)< 0.001
 Pulmonary infection63 (29.6)18 (60.0)0.001
 Cardiovascular disease58 (27.2)20 (66.7)< 0.001
 Neurological diseases47 (22.1)11 (36.7)0.079
 Gastrointestinal pathology56 (26.3)7 (23.3)0.729
 Chronic/acute liver disease36 (16.9)9 (30.0)0.084
 Chronic/acute renal failure74 (34.7)16 (53.3)0.048
 Solid tumour19 (8.9)3 (10.0)0.847
 Haematological malignancy5 (2.3)1 (3.3)0.991
 Severe autoimmune diseases8 (3.8)3 (10.0)0.124
 Diabetes mellitus79 (37.1)14 (46.7)0.312
 Burns5 (2.3)1 (3.3)0.745
 HIV/AIDS11 (5.2)2 (6.7)0.732
 Severe trauma13 (6.1)2 (6.7)0.904
Risk factors (n,%)
 Presence of CVC104 (48.8)14 (46.7)0.825
 Mechanical ventilation67 (31.5)15 (50.0)0.044
 Receipt of corticosteroids58 (27.2)12 (40.0)0.148
 Total parenteral nutrition100 (46.9)19 (63.3)0.093
 Chemotherapy10 (4.7)1 (3.3)0.737
 Abdominal surgery67 (31.5)2 (6.7)0.005
 In the ICU at diagnosis30 (14.1)12 (40.0)< 0.001
 Neutropenia5 (2.3)2 (6.7)0.185
 Concomitant bacterial infections67 (31.5)14 (46.7)0.098
 Septic shock35 (16.4)11 (36.7)0.008
 Dialysis21 (9.9)4 (13.3)0.558
 Prior exposure to broad-spectrum antibiotics188 (88.3)27 (90.0)0.780
 Treatment with antifungal agents71 (33.3)12 (40.0)0.471
Species, n (%)
C. albicans90 (42.3)20 (66.7)0.012
C. glabrata67 (31.5)6 (20.0)0.200
C. tropicalis34 (16.0)3 (10.0)0.395
  1. ICU intensive care unit, CVC central venous catheter
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