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Table 1 Patient characteristics and incidence (episode/1000 admission)

From: Surveillance study of the prevalence, species distribution, antifungal susceptibility, risk factors and mortality of invasive candidiasis in a tertiary teaching hospital in Southwest China

 Candida species
TotalC. albicansC. glabrataC. tropicalisC. kruseiC. parapsilosisOthersh
(n = 243)
100.0%
(n = 110)
45.3%
(n = 73)
30.0%
(n = 37)
15.2%
(n = 12)
4.9%
(n = 5)
2.1%
(n = 6)
2.5%
Patient characteristics
 Age (years)
  16–4970 (28.8)32 (45.7)23 (32.8)8 (11.4)3 (4.3)2 (2.9)2 (2.9)
  50–6584 (34.6)24 (28.6)35 (41.6)15 (17.9)6 (7.1)2 (2.4)2 (2.4)
   > 6589 (36.6)54 (60.7)15 (16.9)14 (15.7)3 (3.4)1 (1.1)2 (2.2)
 Gender
  Male139 (57.2)60 (43.2)41 (29.5)28 (20.1)4 (2.9)4 (2.9)2 (1.4)
  Female10 4 (42.8)50 (48.1)32 (30.8)9 (8.7)8 (7.7)1 (0.9)4 (3.8)
 Underlying comorbidities (n, %)
  Gastrointestinal perforation48 (19.6)24 (50.0)10 (20.8)8 (16.7)5 (10.4)0 (0)1 (2.1)
  Respiratory dysfunctiona51 (21.0)25 (49.0)16 (31.4)9 (17.6)0 (0)0 (0)1 (2.0)
  Pulmonary infection81 (33.3)43 (53.1)20 (24.7)14 (17.3)1 (1.2)1 (1.2)2 (2.5)
  Cardiovascular disease78 (32.1)41 (52.6)20 (25.6)10 (12.8)5 (6.4)0 (0)2 (2.6)
  Neurological diseases58 (23.9)35 (60.4)10 (17.2)9 (15.5)2 (3.5)1 (1.7)1 (1.7)
  Gastrointestinal pathologyb63 (25.9)32 (50.8)18 (28.6)7 (11.1)5 (7.9)1 (1.6)0 (0)
  Chronic/acute liver disease45 (18.5)22 (48.9)9 (0.2)10 (22.2)3 (6.7)1 (2.2)0 (0)
  Chronic/acute renal failurec90 (37.0)48 (53.3)23 (25.6)15 (16.7)2 (2.2)0 (0)2 (2.2)
  Solid tumour22 (9.1)11 (50.0)2 (9.1)7 (31.8)2 (9.1)0 (0)0 (0)
  Haematological malignancy6 (2.5)3 (50.0)1 (16.7)1 (16.7)0 (0)0 (0)1 (16.6)
  Severe autoimmune diseases11 (4.5)7 (63.6)0 (0)3 (27.3)1 (9.1)0 (0)0 (0)
  Diabetes mellitus93 (38.3)57 (61.3)19 (20.4)11 (11.8)6 (6.5)0 (0)0 (0)
  Burns6 (2.5)2 (33.3)1 (16.7)1 (16.7)0 (0)2 (33.3)0 (0)
  HIV/AIDS13 (5.3)2 (15.4)10 (76.9)0 (0)0 (0)0 (0)1 (7.7)
  Severe trauma15 (6.2)6 (40.0)3 (20.0)4 (26.6)1 (6.7)1 (6.7)0 (0)
 Risk factors (n, %)
  Presence of CVCd118 (48.6)59 (50.0)23 (19.5)24 (20.3)8 (6.8)2 (1.7)2 (1.7)
  Mechanical ventilation82 (33.7)41 (50.0)19 (23.2)15 (18.3)5 (6.1)1 (1.2)1 (1.2)
  Receipt of corticosteroidse70 (28.8)43 (61.4)12 (17.1)14 (20.0)1 (1.4)0 (0)0 (0)
  Total parenteral nutrition119 (49.0)62 (52.1)29 (24.4)19 (16.0)7 (5.9)1 (0.8)1 (0.8)
  Chemotherapy11 (4.5)4 (36.4)1 (9.1)5 (45.4)1 (9.1)0 (0)0 (0)
  Abdominal surgeryf69 (28.4)26 (37.7)27 (39.1)10 (14.5)4 (5.8)0 (0)2 (2.9)
  Intensive care in adults42 (17.3)21 (50.0)9 (21.4)8 (19.0)2 (4.8)1 (2.4)1 (2.4)
  Neutropeniag7 (2.9)4 (57.1)0 (0)1 (14.3)2 (28.6)0 (0)0 (0)
  Concomitant bacterial infections81 (33.3)46 (56.8)13 (16.0)18 (22.3)2 (2.5)1 (1.2)1 (1.2)
  Septic shock46 (18.9)16 (34.8)19 (41.4)7 (15.2)2 (4.3)0 (0)2 (4.3)
  Dialysis25 (10.3)9 (36.0)13 (52.0)2 (8.0)0 (0)0 (0)1 (4.0)
 Previous antibiotics therapy215 (88.5)103 (47.9)60 (27.9)35 (16.3)12 (5.6)1 (0.5)4 (1.8)
  Treatment with antifungal agents83 (34.2)44 (53.0)20 (24.1)14 (16.9)3 (3.6)0 (0)2 (2.4)
 Incidence (episodes/1000 admissions)
  20130.160.050.060.030.0100.01
  20140.310.160.070.060.0100.01
  20150.430.180.130.060.040.020
  20160.520.280.130.050.0300.03
  20170.660.250.230.120.020.030.01
  1. aIncludes the following diseases: chronic obstructive pulmonary disease and acute respiratory distress syndrome
  2. bIncludes the following diseases: cholecystitis, pancreatitis, and peritonitis
  3. cChronic/Acute renal failure is the permanent or sudden and often temporary loss of kidney function with N waste retention and hypourocrinia
  4. dCVC central venous catheter
  5. ea dose equivalent to the prednisone dosage of 0.3 mg/kg/day for at least 14 days
  6. fincluding: gastrointestinal perforations, severe acute pancreatitis and complex ventral hernia
  7. gNeutropenia is the absolute neutrophil count, that is, < 500 cells/μl
  8. hOthers include C. guilliermondii (3), C. haemulonii (2) and C. pseudotropicalis (1)