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Table 2 Comparison of different diagnostic tests for patients with active tuberculosis infection at University of Texas MD Anderson Cancer Center from 2006 to 2014

From: Active Mycobacterium tuberculosis infection at a comprehensive cancer center, 2006–2014

Patients Without cancer diagnosis
N = 20 (%)
With cancer diagnosis
N = 32 (%)
Positive AFB smear 5 (25) 6 (19)
Positive TB Culture 20 (100) 32 (100)
Sputum 1 (5) 6 (19)
BAL 6 (30) 9 (28)
FNA 2 (10) 9 (28)
Tissue 11 (55) 8 (25)
Positive TB PCRa 1 1
Positive IGRA 7/8b (88) 9/16c (56)
T-SPOT.TB 0 1
QFT.TB 7 8
Negative IGRA 1/8b (13) 3/16c (19)
T-SPOT.TB 1 0
QTF.TB 0 3
Inconclusive IGRA 0 4/16c (25)
T-SPOT.TB 0 0
QTF.TB 0 4
  1. a 3 TB PCR were performed
  2. b 8 in non-cancer patients
  3. c 16 cancer patients
  4. Abbreviations: AFB, Acid fast bacilli; TB, tuberculosis; BAL, bronchoalveolar lavage; FNA, fine needle aspirate; PCR, polymerase chain reaction; IGRA, interferon gamma release assay; QFT, QuantiFERON