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Table 1 Characteristics and outcomes of patients with active tuberculosis infection with or without cancer diagnosis at University of Texas MD Anderson Cancer Center from 2006 to 2014

From: Active Mycobacterium tuberculosis infection at a comprehensive cancer center, 2006–2014

Characteristic

Without cancer diagnosis

n = 20 (%)

With cancer diagnosis

n = 32 (%)

p value

Age

53 (16–78)

61 (33–85)

0.016

Gender

 Male

11 (55)

25 (78)

0.067

 Female

9 (45)

7 (22)

 

Race

  

0.213

 White

4 (20)

9 (28)

 

 Black

0

5 (16)

 

 Hispanic

5 (25)

5 (16)

 

 Asian

11 (55)

13 (40)

 

Underlying conditions

   

 Solid Tumor

_

18 (56)

 

 Leukemia

_

6 (19)

 

 Lymphoma

_

2 (6)

 

 Hematopoetic cell transplantation

_

6 (19)

 

 Suspicion for cancer

17 (85%)

_

 

 Human Immunodeficiency Virus

1 (5%)

_

 

 Psoriasis

1 (5%)

_

 

 Healthcare worker

1 (5%)

_

 

Cancer Status

 Active disease

_

16 (50)

 

 Complete remission

_

15 (47)

 

 Partial remission

_

1 (3)

 

 Corticosteroid use

3 (15)

7 (22)

0.541

 Chemotherapy/Immunosuppressants

1 (5)a

19 (59)

 

 Endemic region for Tuberculosis

14 (70)

15 (47)

0.15

History of exposure to Tuberculosis

  

0.47

 Yes

8 (40)

10 (31)

 

 Probable

3 (15)

3 (9)

 

Previous treatment of latent Tuberculosis

 

3d

3e

 

Site of infection

  

0.84

  Pulmonary

12 (60)

20 (60)

 

 Extrapulmonary

5 (25)

5 (16)

 

 Lymph nodes

3 (15)

4 (13)

 

 Peritoneum

1 (5)

_

 

 Bones and joints

1 (5)

_

 

 Otherb

_

1 (5)

 

 Disseminated

3 (15)

7 (22)

 

Radiologic findingsc

 Cavitary

5 (25)

6 (19)

0.591

 Nodular

9 (45)

15 (47)

0.895

 Death

0

11 (34)

0.0036

 Attributed to Tuberculosis

0

3 (27)

0.276

  1. aImmunomodulators for psoriasis
  2. bPelvic mass
  3. cChest imaging available for 24 patients
  4. d2 complete, 1 incomplete
  5. e1 complete, 2 incomplete