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Table 1 Characteristics and outcomes of patients with active tuberculosis infection with or without cancer diagnosis at University of Texas MD Anderson Cancer Center from 2006 to 2014

From: Active Mycobacterium tuberculosis infection at a comprehensive cancer center, 2006–2014

Characteristic Without cancer diagnosis
n = 20 (%)
With cancer diagnosis
n = 32 (%)
p value
Age 53 (16–78) 61 (33–85) 0.016
Gender
 Male 11 (55) 25 (78) 0.067
 Female 9 (45) 7 (22)  
Race    0.213
 White 4 (20) 9 (28)  
 Black 0 5 (16)  
 Hispanic 5 (25) 5 (16)  
 Asian 11 (55) 13 (40)  
Underlying conditions    
 Solid Tumor _ 18 (56)  
 Leukemia _ 6 (19)  
 Lymphoma _ 2 (6)  
 Hematopoetic cell transplantation _ 6 (19)  
 Suspicion for cancer 17 (85%) _  
 Human Immunodeficiency Virus 1 (5%) _  
 Psoriasis 1 (5%) _  
 Healthcare worker 1 (5%) _  
Cancer Status
 Active disease _ 16 (50)  
 Complete remission _ 15 (47)  
 Partial remission _ 1 (3)  
 Corticosteroid use 3 (15) 7 (22) 0.541
 Chemotherapy/Immunosuppressants 1 (5)a 19 (59)  
 Endemic region for Tuberculosis 14 (70) 15 (47) 0.15
History of exposure to Tuberculosis    0.47
 Yes 8 (40) 10 (31)  
 Probable 3 (15) 3 (9)  
Previous treatment of latent Tuberculosis
  3d 3e  
Site of infection    0.84
  Pulmonary 12 (60) 20 (60)  
 Extrapulmonary 5 (25) 5 (16)  
 Lymph nodes 3 (15) 4 (13)  
 Peritoneum 1 (5) _  
 Bones and joints 1 (5) _  
 Otherb _ 1 (5)  
 Disseminated 3 (15) 7 (22)  
Radiologic findingsc
 Cavitary 5 (25) 6 (19) 0.591
 Nodular 9 (45) 15 (47) 0.895
 Death 0 11 (34) 0.0036
 Attributed to Tuberculosis 0 3 (27) 0.276
  1. aImmunomodulators for psoriasis
  2. bPelvic mass
  3. cChest imaging available for 24 patients
  4. d2 complete, 1 incomplete
  5. e1 complete, 2 incomplete