Transmission and serotype features of hand foot mouth disease in household contacts in Dong Thap, Vietnam

BMC Infectious Diseases

Table 2 Factors associated with EV infection in index cases

Characteristics	Laboratory confirmed^x (n=113)	Not Laboratory confirmed (n=37)	Crude RR [cRR]	95% CI [CI]	P-value
Sex
Female	50 (71)	20 (29)	1.00	[0.63,
Male	63 (79)	17 (21)	0.91	1.31]	0.61
Age
<1 year	32 (72)	12 (28)	1.00
1-<3 years	71 (78)	20 (22)	1.07	[0.71, 1.63]	0.74
3+ years	10 (67)	5 (33)	0.92	[0.45, 1.86]	0.81
Household size^!
<5	44 (73)	16 (27)	1.00
≥5	69 (77)	21 (23)	1.05	[0.72, 1.53]	0.82
Number of children in household
<2	84 (76)	26 (24)	1.00
2+	29 (73)	11 (27)	0.95	[0.62, 1.45]	0.81
Toy sharing^~
No	84 (78)	24 (22)	1.00
Yes	29 (69)	13 (31)	1.13	[0.74, 1.72]	0.58
Boiled water
No	13 (75)	4 (25)	1.00
Yes	100 (75)	33 (25)	1.02	[0.57, 1.81]	0.95
Homemade food
No	39 (83)	8 (17)	1.00
Yes	74 (72)	29 (28)	1.15	[0.78, 1.70]	0.47

^X Defined as a positive RT-PCR, or a 4-fold change in a single EV-A71, CV-A6, CV-A16 (or more) serotype neutralizing antibody titers between sample 1 and sample 2.
^! Mean household size 5 people.
^~ Defined as either index case or household contact (≤15yrs) stating yes to toy sharing.
Values expressed as number (percentage within exposure group) unless otherwise indicated

ISSN: 1471-2334