Table 4 The evaluation of diagnostic tests of syphilitic indicators for neurosyphilis
From: Clinical prediction and diagnosis of neurosyphilis in HIV-negative patients: a case-control study
Variable | Sensitivity (%) | Specificity (%) | AUC & 95% CI | p value |
|---|---|---|---|---|
Neurological symptoms | 46.00 | 89.80 | 0.679 (0.578–0.769) | < 0.001 |
CSF TPPA titer (cutoff > 1:160) | 90.00 | 84.00 | 0.941 (0.876–0.978) | < 0.001 |
CSF protein (cutoff > 497 mg/L) | 54.00 | 85.71 | 0.710 (0.610–0.797) | < 0.001 |
CSF WBC (cutoff > 3 cells/μL) | 48.00 | 82.00 | 0.655 (0.553–0.747) | 0.003 |
A combination of the above tests except CSF TPPA | 92.00 | 33.30 | 0.793(0.700–0.887) | < 0.001 |
A combination of the above tests | 98.00 | 40.80 | 0.786 (0.692–0.880) | < 0.001 |