Clinical prediction and diagnosis of neurosyphilis in HIV-negative patients: a case-control study

BMC Infectious Diseases

Table 2 Predictors of neurosyphilis according to univariable logistic regression

Variable	Coefficient	OR	95% CI	p value
Neurological symptoms	2.014	7.496	2.547–22.059	< 0.001
Serum TRUST titer	0.014	1.014	0.992–1.036	0.211
Serum TPPA titer	0.003	1.003	1.000–1.006	0.030
Serum TP-IgM	1.127	3.088	1.157–8.241	0.024
CSF TPPA titer	0.004	1.004	1.003–1.005	< 0.001
CSF protein	0.004	1.004	1.002–1.006	0.001
CSF WBC	0.071	1.074	1.002–1.152	0.045
CSF glucose	−0.072	0.931	0.620–1.398	0.729
CSF chlorides	−0.111	0.895	0.820–0.976	0.012

OR Odds ratio, CI Confidence interval, TRUST Serum toludine red unheated serum test, TPPA Treponema pallidum particle agglutination, TP-IgM Treponema pallidum IgM, CSF Cerebrospinal fluid, WBC White blood cell

ISSN: 1471-2334