Table 2 Univariable and multivariable logistic regression models of factors associated with Epstein-Barr Virus seropositivity in England in 2002
From: Predictors of Epstein-Barr virus serostatus in young people in England
Univariable | Multivariable (whole population) | Multivariable (adults only) | ||||
|---|---|---|---|---|---|---|
OR (95% CI) | P value | aOR (95% CI) | P value | aOR (95% CI) | P value | |
Sex | ||||||
Male | 1.00 | 1.00 | 1.00 | |||
Female | 1.24 (0.87–1.75) | 0.230 | 1.15 (0.79–1.67) | 0.454 | 1.47 (0.86–2.53) | 0.156 |
Age group (years) | ||||||
11–14 | 1.00 | 1.00 | ||||
15–18† | 1.43 (0.97–2.11) | 0.068 | 1.52 (1.01–2.30) | 0.046 | 1.00 | |
19–21 | 3.61 (2.13–6.13) | < 0.001 | 3.76 (2.16–6.57) | < 0.001 | 2.51 (1.31–4.82) | 0.006 |
22–24 | 8.76 (4.30–17.83) | < 0.001 | 9.16 (4.38–19.14) | < 0.001 | 6.14 (2.64–14.27) | < 0.001 |
Ethnicity | ||||||
White | 1.00 | 1.00 | 1.00 | |||
Other | 1.93 (1.04–3.60) | 0.038 | 2.33 (1.13–4.78) | 0.021 | 4.26 (1.03–17.58) | 0.045 |
BMI | ||||||
Healthy weight | 1.00 | 1.00 | 1.00 | |||
Underweight | 1.46 (0.77–2.77) | 0.243 | 1.13 (0.59–2.17) | 0.718 | 1.13 (0.55–2.32) | 0.731 |
Overweight | 1.55 (0.97–2.49) | 0.070 | 1.16 (0.69–1.95) | 0.567 | 1.93 (0.88–4.24) | 0.101 |
Obese | 1.18 (0.65–2.13) | 0.588 | 1.25 (0.67–2.33) | 0.483 | 1.47 (0.45–4.77) | 0.517 |
Region of UK | ||||||
East of England | 1.00 | 1.00 | 1.00 | |||
North East | 2.16 (0.73–6.43) | 0.166 | 2.46 (0.83–7.30) | 0.105 | 4.78 (0.98–23.19) | 0.052 |
North West | 1.59 (0.82–3.10) | 0.169 | 1.92 (0.94–3.90) | 0.072 | 1.28 (0.55–2.99) | 0.570 |
Yorkshire and The Humber | 3.11 (1.41–6.84) | 0.005 | 3.11 (1.39–6.98) | 0.006 | 1.90 (0.73–4.95) | 0.187 |
East Midlands | 1.92 (0.87–4.20) | 0.104 | 2.38 (1.06–5.33) | 0.035 | 1.80 (0.67–4.87) | 0.243 |
West Midlands | 1.03 (0.50–2.10) | 0.934 | 1.34 (0.63–2.86) | 0.450 | 0.96 (0.28–3.26) | 0.946 |
London | 2.01 (0.90–4.52) | 0.090 | 1.42 (0.61–3.29) | 0.415 | 1.10 (0.37–3.24) | 0.866 |
South East | 1.51 (0.76–3.03) | 0.242 | 1.84 (0.89–3.79) | 0.099 | 1.27 (0.53–3.03) | 0.589 |
South West | 1.73 (0.87–3.43) | 0.118 | 1.97 (0.93–4.17) | 0.077 | 2.84 (0.87–9.24) | 0.082 |
CMV serostatus | ||||||
Seronegative | 1.00 | 1.00 | 1.00 | |||
Seropositive | 1.59 (1.06–2.39) | 0.026 | 1.25 (0.79–1.98) | 0.337 | 2.16 (1.05–4.43) | 0.036 |
Smoking statusa | ||||||
Never smoked | 1.00 | – | – | 1.00 | ||
Current smoker | 4.40 (2.22–8.73) | < 0.001 | – | – | 4.29 (2.13–8.65) | < 0.001 |
Smoked in past | 1.92 (1.09–3.40) | 0.025 | – | – | 1.94 (0.99–3.81) | 0.054 |
Occupational categorya | ||||||
Higher managerial and professional | 1.00 | < 0.001 | – | – | 1.00 | |
Intermediate occupations | 1.23 (0.43–3.53) | 0.695 | – | – | 1.54 (0.47–5.03) | 0.469 |
Routine and manual occupations | 0.64 (0.30–1.36) | 0.245 | – | – | 1.41 (0.62–3.22) | 0.416 |
Never worked or long-term unemployed | 1.70 (0.19–14.82) | 0.631 | – | – | 3.16 (0.22–45.85) | 0.397 |
Other | 0.72 (0.26–2.03) | 0.533 | – | – | 1.93 (0.56–6.69) | 0.297 |