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Table 2 Univariable and multivariable logistic regression models of factors associated with Epstein-Barr Virus seropositivity in England in 2002

From: Predictors of Epstein-Barr virus serostatus in young people in England

 UnivariableMultivariable (whole population)Multivariable (adults only)
 OR (95% CI)P valueaOR (95% CI)P valueaOR (95% CI)P value
Sex 
 Male1.00 1.00 1.00 
 Female1.24 (0.87–1.75)0.2301.15 (0.79–1.67)0.4541.47 (0.86–2.53)0.156
Age group (years)
 11–141.00 1.00   
 15–18†1.43 (0.97–2.11)0.0681.52 (1.01–2.30)0.0461.00 
 19–213.61 (2.13–6.13)< 0.0013.76 (2.16–6.57)< 0.0012.51 (1.31–4.82)0.006
 22–248.76 (4.30–17.83)< 0.0019.16 (4.38–19.14)< 0.0016.14 (2.64–14.27)< 0.001
Ethnicity 
 White1.00 1.00 1.00 
 Other1.93 (1.04–3.60)0.0382.33 (1.13–4.78)0.0214.26 (1.03–17.58)0.045
BMI
 Healthy weight1.00 1.00 1.00 
 Underweight1.46 (0.77–2.77)0.2431.13 (0.59–2.17)0.7181.13 (0.55–2.32)0.731
 Overweight1.55 (0.97–2.49)0.0701.16 (0.69–1.95)0.5671.93 (0.88–4.24)0.101
 Obese1.18 (0.65–2.13)0.5881.25 (0.67–2.33)0.4831.47 (0.45–4.77)0.517
Region of UK 
 East of England1.00 1.00 1.00 
 North East2.16 (0.73–6.43)0.1662.46 (0.83–7.30)0.1054.78 (0.98–23.19)0.052
 North West1.59 (0.82–3.10)0.1691.92 (0.94–3.90)0.0721.28 (0.55–2.99)0.570
 Yorkshire and The Humber3.11 (1.41–6.84)0.0053.11 (1.39–6.98)0.0061.90 (0.73–4.95)0.187
 East Midlands1.92 (0.87–4.20)0.1042.38 (1.06–5.33)0.0351.80 (0.67–4.87)0.243
 West Midlands1.03 (0.50–2.10)0.9341.34 (0.63–2.86)0.4500.96 (0.28–3.26)0.946
 London2.01 (0.90–4.52)0.0901.42 (0.61–3.29)0.4151.10 (0.37–3.24)0.866
 South East1.51 (0.76–3.03)0.2421.84 (0.89–3.79)0.0991.27 (0.53–3.03)0.589
 South West1.73 (0.87–3.43)0.1181.97 (0.93–4.17)0.0772.84 (0.87–9.24)0.082
CMV serostatus
 Seronegative1.00 1.00 1.00 
 Seropositive1.59 (1.06–2.39)0.0261.25 (0.79–1.98)0.3372.16 (1.05–4.43)0.036
Smoking statusa 
 Never smoked1.00 1.00 
 Current smoker4.40 (2.22–8.73)< 0.0014.29 (2.13–8.65)< 0.001
 Smoked in past1.92 (1.09–3.40)0.0251.94 (0.99–3.81)0.054
Occupational categorya 
 Higher managerial and professional1.00< 0.0011.00 
 Intermediate occupations1.23 (0.43–3.53)0.6951.54 (0.47–5.03)0.469
 Routine and manual occupations0.64 (0.30–1.36)0.2451.41 (0.62–3.22)0.416
 Never worked or long-term unemployed1.70 (0.19–14.82)0.6313.16 (0.22–45.85)0.397
 Other0.72 (0.26–2.03)0.5331.93 (0.56–6.69)0.297
  1. aAdults aged ≥16 years only (n = 472). †16–18 years for ‘adult-only’ model. Odds ratios account for the weighting of the sample to be representative of the English population in 2002 with respect to age and sex. The ‘whole population’ multivariable model included age, sex, CMV serostatus, ethnicity, BMI and region of England. The ‘adults only’ multivariable model included all variables shown in the table. aOR adjusted odds ratio, BMI body mass index, CI confidence interval, CMV cytomegalovirus, OR unadjusted odds ratio