Skip to main content

Table 3 Multivariable logistic regression analyses of the association between premature delivery and clinical course and treatment of pertussis; crude and adjusted OR and 95% confidence intervals (95%CI)

From: Pertussis hospitalizations among term and preterm infants: clinical course and vaccine effectiveness

  Probable and certain term infants (n = 596)a,b Preterm infants (n = 80)b Crude OR (95% CI) Adjusted OR (95% CI)c
Symptoms at admission
 Coughing attacks 438 (73.5%) 56 (70.0%) 0.8 (0.5–1.4) 0.8 (0.5–1.4)
 Apnea 92 (15.4%) 18 (22.5%) 1.6 (0.9–2.8) 1.8 (1.0–3.3)
 Whooping 23 (3.9%) 1 (1.3%) 0.3 (0.04–2.4) 0.3 (0.04–2.3)
 Vomiting 210 (35.2%) 28 (35.0%) 1.0 (0.6–1.6) 1.0 (0.6–1.6)
 Prolonged inspiratory effort 42 (7.1%) 7 (8.8%) 1.3 (0.5–2.9) 1.2 (0.5–2.7)
 Collapse 6 (1.0%) 2 (2.5%) 2.5 (0.5–12.7) 3.8 (0.7–19.7)
 Cyanosis 259 (43.5%) 25 (31.3%) 0.6 (0.4–1.0) 0.7 (0.4–1.1)
 Fever 52 (8.7%) 8 (10.0%) 1.2 (0.5–2.6) 0.9 (0.4–2.0)
 Feeding problems 185 (31.0%) 27 (33.8%) 1.1 (0.7–1.9) 1.1 (0.7–1.9)
Complications
 Any complication 53 (8.9%) 10 (12.5%) 1.5 (0.7–3.0) 1.6 (0.8–3.4)
Treatment
 Antibiotics before admission 114/580 (19.7%) 18/77 (23.4%) 1.1 (0.6–2.0) 1.1 (0.6–1.9)
 Antibiotics during admission 475/587 (80.9%) 68/78 (87.2%) 1.5 (0.7–3.2) 1.8 (0.9–3.9)
 Artificial respiration 39/577 (6.8%) 11/77 (14.3%) 2.3 (1.1–4.8) 2.8 (1.3–6.0)
 Additional oxygen 198/585 (33.9%) 28 (36.8%) 1.1 (0.7–1.9) 1.3 (0.8–2.2)
 Admission intensive care unit (ICU) 59 (9.9%) 10 (12.5%) 1.3 (0.6–2.7) 1.6 (0.8–3.6)
Discharge
 Symptoms remaining 460 (77.2%) 58 (72.5%) 0.8 (0.5–1.3) 0.8 (0.5–1.4)
  1. Term infants are set as reference. Significant results are in bold
  2. aterm infants in main analysis
  3. bIf denominator is different, it is reported in the cell
  4. cadjusted for coinfections and age in months at admission