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Table 2 Factors associated with positive sputum culture after 6 months of anti-TB treatment

From: Viable Mycobacterium tuberculosis in sputum after pulmonary tuberculosis cure

  Sputum status at the end of anti-TB treatment aP-value
Smear negative n/N (%) Culture negative
n/N (%)
Culture positive
n/N (%)
Age, years
 16–35 144/144 (100) 136/144 (94.4) 8/144 (5.6) .708
 36–55 44/44 (100) 40/44 ((90.9) 4/44 (9.1) .999
 56–76 16/16 (100) 16/16 (100) 0/16 (0) .998
Male 94/94 (100) 88/94 (93.6) 6/94 (6.3) .585
Female 109/109 (100) 103/109 (93.5) 6/109 (5.5)  
Smoker 14/204 (6.8) 14/14 (100) 0/14 (0) .999
Diabetes 11/204 (5.3) 11/11 (100) 0/11 (0) .999
bBacillary load before treatment
 Scanty 20/204 (9.8) 18/20 (90.0) 2/20 (10.0) .661
 + 1 117/204 (57.4) 109/117 (93.2) 8/117 (6.8) .382
 + 2 37/204 (18.1) 36/37 (97.3) 1/37 (2.7) .661
 + 3 30/204 (14.7) 29/30 (96.7) 1/30 (3.3) .815
Smear positivity at 2 M 3/204 (1.5) 3/3 (100) 0/3 (0) 1.00
Chest X-ray
 Cavitary lesions 7/102 (6.9) 6/7 (85.7) 1/7 (14.3) .265
 Non-cavitary infiltrates 95/102 (93.1) 91/95 (95.8) 4/95 (4.2)  
History of contact
cRecent 41/204 (20.0) 36/41 (87.8) 5/41 (12.2) .08
dPrevious 39/204 (19.2) 39/39 (100) 0/39 (100) .998
 No history of contact 124/204 (60.8) 119/124 (95.9) 5/124 (4.1) .897
Income
 Low 109/204 (53.4) 102/109 (93.6) 7/109 (6.4) .985
 Middle 9/204 (4.5) 9/9 (100) 0/9 (0) .862
 Unknown 86/204 (42.1) 81/86 (94.2) 5/86 (5.8) .999
Medicines in the continuation Phase
 INH + Rifampicin 103/204 4/103 (3.9) 99/103 (96.1) .177
 INH+ Rifampicin +Ethambutol 101/204 8/101 (7.9) 93/101 (92.1)  
  1. n number, N Total number, % percentage
  2. aDifference between culture positive and culture negative groups
  3. bGraded as per the guidelines of the International Union Against Tuberculosis and Lung Disease
  4. cHistory of contact with active TB case during the course of diagnosis and treatment
  5. dHistory of contact with active TB case before diagnosis and treatment