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Table 2 Factors associated with positive sputum culture after 6 months of anti-TB treatment

From: Viable Mycobacterium tuberculosis in sputum after pulmonary tuberculosis cure

 

Sputum status at the end of anti-TB treatment

aP-value

Smear negative n/N (%)

Culture negative

n/N (%)

Culture positive

n/N (%)

Age, years

 16–35

144/144 (100)

136/144 (94.4)

8/144 (5.6)

.708

 36–55

44/44 (100)

40/44 ((90.9)

4/44 (9.1)

.999

 56–76

16/16 (100)

16/16 (100)

0/16 (0)

.998

Male

94/94 (100)

88/94 (93.6)

6/94 (6.3)

.585

Female

109/109 (100)

103/109 (93.5)

6/109 (5.5)

 

Smoker

14/204 (6.8)

14/14 (100)

0/14 (0)

.999

Diabetes

11/204 (5.3)

11/11 (100)

0/11 (0)

.999

bBacillary load before treatment

 Scanty

20/204 (9.8)

18/20 (90.0)

2/20 (10.0)

.661

 + 1

117/204 (57.4)

109/117 (93.2)

8/117 (6.8)

.382

 + 2

37/204 (18.1)

36/37 (97.3)

1/37 (2.7)

.661

 + 3

30/204 (14.7)

29/30 (96.7)

1/30 (3.3)

.815

Smear positivity at 2 M

3/204 (1.5)

3/3 (100)

0/3 (0)

1.00

Chest X-ray

 Cavitary lesions

7/102 (6.9)

6/7 (85.7)

1/7 (14.3)

.265

 Non-cavitary infiltrates

95/102 (93.1)

91/95 (95.8)

4/95 (4.2)

 

History of contact

 cRecent

41/204 (20.0)

36/41 (87.8)

5/41 (12.2)

.08

 dPrevious

39/204 (19.2)

39/39 (100)

0/39 (100)

.998

 No history of contact

124/204 (60.8)

119/124 (95.9)

5/124 (4.1)

.897

Income

 Low

109/204 (53.4)

102/109 (93.6)

7/109 (6.4)

.985

 Middle

9/204 (4.5)

9/9 (100)

0/9 (0)

.862

 Unknown

86/204 (42.1)

81/86 (94.2)

5/86 (5.8)

.999

Medicines in the continuation Phase

 INH + Rifampicin

103/204

4/103 (3.9)

99/103 (96.1)

.177

 INH+ Rifampicin +Ethambutol

101/204

8/101 (7.9)

93/101 (92.1)

 
  1. n number, N Total number, % percentage
  2. aDifference between culture positive and culture negative groups
  3. bGraded as per the guidelines of the International Union Against Tuberculosis and Lung Disease
  4. cHistory of contact with active TB case during the course of diagnosis and treatment
  5. dHistory of contact with active TB case before diagnosis and treatment