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Table 5 Risk ratios for failure to obtain a TST result by demographic and clinical characteristic. Results are presented for complete case analysis (n = 1878 patientsa) and analysis using combined results of 20 imputed datasets (n = 2303 patients). RRs marked with an asterisk (*) are statistically significant. CI = confidence interval

From: The latent tuberculosis infection cascade of care in Iqaluit, Nunavut, 2012–2016

Potential Risk factor Patients with no TST results/ category total (%) Risk ratio from univariate modelsb (95% CI) Adjusted risk ratioc (95% CI), complete case Adjusted risk ratioc (95% CI), multiple imputation
Age, years (per 5-year increase) 0.98 (0.95–1.02)
Sex
 Male 69/1065 (6.5%) Reference
 Female 61/1238 (4.9%) 0.87 (0.67–1.13)
Ethnicity
 Inuit 48/1220 (3.9%) Reference Reference Reference
 Non-Inuit 28/658 (4.3%) 0.76 (0.54–1.06) 0.68 (0.47–0.98)* 0.79 (0.58–1.06)
Indication for TST
 Tuberculosis exposure 20/606 (3.3%) Reference Reference Reference
 Employment screening 26/506 (5.1%) 1.22 (0.82–1.83) 1.08 (0.65–1.78) 1.16 (0.77–1.76)
 School screening 25/297 (8.4%) 1.52 (0.95–2.42) 1.26 (0.68–2.29) 1.32 (0.83–2.11)
 Self or physician referral 45/746 (6.0%) 1.72 (1.22–2.42)* 1.65 (1.12–2.44)* 1.64 (1.17–2.30)*
Year of TST
 2012 28/759 (3.7%) Reference Reference Reference
 2013 29/547 (5.3%) 1.27 (0.88–1.83) 1.38 (0.88–2.16) 1.25 (0.87–1.81)
 2014 31/498 (6.2%) 1.18 (0.80–1.74) 1.08 (0.65–1.79) 1.16 (0.79–1.71)
 2015 36/425 (8.5%) 1.52 (1.05–2.19)* 1.19 (0.70–2.02) 1.52 (1.04–2.22)*
 2016 6/74 (8.1%) 1.76 (0.93–3.34) 1.98 (0.94–4.15) 1.71 (0.91–3.21)
  1. aData regarding ethnicity were missing for 472 TSTs (14.9%) in 425 patients (18.5%) and were estimated using multiple imputation. Data on indication were missing for 189 TSTs (6.0%) in 148 patients (6.4%)
  2. bUnivariate models adjusted for the correlation between multiple TSTs performed on the same individual using an exchangeable correlation matrix
  3. cModel included ethnicity, indication for TST and year of TST and adjusted for the correlation between multiple TSTs performed on the same individual using an exchangeable correlation matrix