Table 1 Disseminated histoplasmosis involved in digestive tract in immunocompetent individuals
Articles | Country | Gender | Age | Symptoms | Involvement | Intervention | Prognosis |
|---|---|---|---|---|---|---|---|
Yang 2013 [5] | China | Male | 33 | Fever, weight loss | Bone marrow, spleen, colon | Amphotericin B deoxycholate for a total of 2 g, shifted to oral itraconazole (200 mg bid) | Recovery |
Badyal 2013 [6] | India | Male | 62 | Abdominal distension, abdominal pain, constipation | Colon | Tazocin 4.5 g and metronidazole 500 mg q8h, amphotericin B 500 mg and itraconazole 200 mg qd for 15 days | Recovery |
Chaudhari 2013 [7] | USA | Female | 22 | Fever, weight loss, dysphagia, | Esophagus | Thoracotomy | Recovery |
Wu 2015 [2] | China | Male | 29 | Fever, cough | Colon | Not reported | Not reported |
Zhu 2016 [8] | China | Male | 61 | Abdominal pain, abdominal distention, anorexia | Colon | No anti-fungal drugs | Recovery |
|  |  | Male | 33 | Fever, anorexia, pharyngalgia, cough, expectoration, weight loss | Bone marrow, colon, terminal ileum | Amphotericin B deoxycholate for a total of 1.47–2.79 g, shifted to itraconazole (200 mg bid) for 6 m | Recovery |
|  |  | Male | 59 | Fever, abdominal pain, abdominal distention, anorexia, weight loss | Bone marrow, colon, terminal ileum | Amphotericin B deoxycholate for a total of 1.47–2.79 g, shifted to itraconazole (200 mg bid) for 6 m | Recovery |
|  |  | Male | 28 | Fever, abdominal pain, abdominal distention, diarrhea, weight loss | Bone marrow, colon, terminal ileum | Amphotericin B deoxycholate for a total of 1.47–2.79 g, shifted to itraconazole (200 mg bid) for 6 m | Lost |
Sharma 2017 [9] | India | Male | 45 | Right-sided pleural effusion | Lung, ileum | Amphotericin B deoxycholate, details not reported | Recovery |