Fig. 1

shows the evolution of monocyte HLA-DR expression. Figure 1a (cohort A) depicts the individual data of mHLA-DR expression (AB/C event/cell) before and within the 24 h after stopping IFNγ treatment, showing the real delay from the admission to be treated. The dotted line figures the threshold below which the immunodepression is identified. Among the 13 patients, 4 increased the HLA-DR expression but did not reach the defined threshold. The X axis: days from admission; the Y axis represents the quantitative AB/C values of mHLA-DR expression. Figure 1b (cohort B) shows similar representation: the X axis: days were IFNγ treatment was administered; Y axis represents the MFI level