Table 3 Changes of characteristics of severe HFMD caused by EV71 in the non-CVVHDF group and the CVVHDF group
Variables | Non-CVVHDF group (nā=ā12) | CVVHDF group (nā=ā17) | Pā | ||||
|---|---|---|---|---|---|---|---|
1st day (A1) | 3rd day (A2) | P | Before CVVHDF (B1) | 72āh after CVVHDF (B2) | Pā | ||
Vital signs | |||||||
āHeart rate, bpm | 188.0 (170.8, 194.8) | 142.0 (130.3, 157.0) | 0.001 | 187.0 (178.0, 197.5) | 134.0 (122.5, 147.0) | 0.001 | 0.143 |
āBody temperature, oC | 39.7 (39.4, 39.8) | 38.0 (37.3, 38.5) | 0.001 | 39.7 (39.3, 40.0) | 36.8 (36.4, 37.3) | 0.001 | 0.001 |
āSystolic blood pressure, mmHg | 132.0 (76.0, 150.5) | 121.5 (103.5, 140.3) | 0.854 | 139 (101.5, 155.0) | 102.5 (86.5, 115.7) | 0.003 | 0.001 |
Cardiac parameters | |||||||
āLVEF, % | 38 (26, 44) | 41 (29, 46) | 0.204 | 37 (21, 47) | 55 (21, 62) | 0.017 | 0.184 |
āCI, L/min/m2 | 2.89 (2.23, 3.63) | 3.11 (2.22, 3.73) | 0.621 | 2.73 (1.92, 3.95) | 4.77 (1.92, 5.75) | 0.002 | 0.199 |
ācTnI, Ī¼g/L | 0.16 (0.06, 0.38) | 0.08 (0.04, 0.15) | 0.032 | 0.12 (0.06, 0.39) | 0.02 (0.01, 0.48) | 0.365 | 0.325 |
āCK-MB, IU/L | 35.0 (20.5, 72.8) | 33.0 (19.0, 64.3) | 0.240 | 37.0 (25.5, 112.0) | 78.0 (39.0, 110.5) | 0.298 | 0.008 |
Organ function indexes | |||||||
āBlood glucose, mg/dL | 9.85 (6.98, 12.18) | 7.9 (6.95, 10.35) | 0.311 | 9.4 (7.9, 11.3) | 6.1 (5.7, 11.8) | 0.118 | 0.057 |
āLac, mmol/L | 4.35 (3.20, 5.80) | 2.2 (1.93, 3.75) | 0.014 | 3.50 (2.75, 3.90) | 1.3 (0.95, 1.90) | 0.001 | 0.005 |
āpH | 7.21 (6.94, 7.37) | 7.31 (7.21, 7.38) | 0.015 | 7.23 (7.07, 7.31) | 7.39 (7.37, 7.44) | 0.001 | 0.041 |
āCr, Ī¼mol/L | 58.0 (28.5, 79.8) | 61.0 (54.5, 119.5) | 0.121 | 48.0 (28.0, 77.0) | 38.0 (20.5, 72.0) | 0.517 | 0.023 |
āALT, IU/L | 36.0 (19.8, 63.3) | 63.0 (27.0, 140.8) | 0.048 | 35.0 (12.5, 70.0) | 38.0 (26.0, 52.0) | 0.227 | 0.170 |
Catecholamine | |||||||
āAdrenalin, ng/L | 153.6 (127.0, 184.4) | 145.4 (85.8, 175.1) | 0.190 | 169.8 (145.5, 244.6) | 148.0 (109.0, 208.1) | 0.033 | 0.223 |
āDopamine, ng/L | 127 (82.4, 156.5) | 133.4 (83.0, 171.7) | 0.678 | 152.7 (97.0, 191.1) | 96.0 (68.0, 160.9) | 0.026 | 0.319 |
RAAS substances | |||||||
āRenin, Ī¼g/L.h | 2.35 (1.49, 4.76) | 2.90 (1.30, 4.80) | 0.872 | 1.12 (0.74, 3.45) | 0.79 (0.52, 1.25) | 0.029 | 0.003 |
āAngiotensinII, ng/L | 348.4 (131.5, 773.0) | 565.4 (210.9, 773.3) | 0.215 | 185.9 (125.2, 800.0) | 106.0 (90.8, 232.5) | 0.047 | 0.001 |
āAldosterone, ng/L | 211.2 (119.8, 362.6) | 281.9 (167.9, 349.0) | 0.730 | 165.7 (94.0, 353.3) | 103.3 (84.3, 144.3) | 0.033 | 0.001 |