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Table 4 Cumulative effects of combined risk alleles (rs1535045 T and rs1883832 T) on the susceptibility to HCV infection

From: CD40 polymorphisms were associated with HCV infection susceptibility among Chinese population

Variables

Group A

Group B+ Group C

Group (B + C)/Group A

n

n

OR(95%CI)a

P a

0

154

123

1

 

1

619

444

0.965 (0.734-1.269)

0.799

2

615

550

1.179 (0.899-1.546)

0.233

3 4

29

64

1.947 (1.741-2.179)

<0.001

Trend

   

<0.001 b

0

154

123

1

 

1-4

1362

1138

1.114 (0.862-1.440)

0.411

  1. Abbreviations: HCV hepatitis C virus, OR odds ratio,95% CI 95% confidence interval
  2. Group A: controls; Group B: spontaneous clearance subjects; Group C: persistent infection patients. Group (B + C): HCV-infected individuals
  3. aLogistic regression model, adjusted for gender, age, and routes of infection
  4. bCochran–Armitage trend test
  5. Bold type indicates statistically significant results