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Table 4 Cumulative effects of combined risk alleles (rs1535045 T and rs1883832 T) on the susceptibility to HCV infection

From: CD40 polymorphisms were associated with HCV infection susceptibility among Chinese population

Variables Group A Group B+ Group C Group (B + C)/Group A
n n OR(95%CI)a P a
0 154 123 1  
1 619 444 0.965 (0.734-1.269) 0.799
2 615 550 1.179 (0.899-1.546) 0.233
3 4 29 64 1.947 (1.741-2.179) <0.001
Trend     <0.001 b
0 154 123 1  
1-4 1362 1138 1.114 (0.862-1.440) 0.411
  1. Abbreviations: HCV hepatitis C virus, OR odds ratio,95% CI 95% confidence interval
  2. Group A: controls; Group B: spontaneous clearance subjects; Group C: persistent infection patients. Group (B + C): HCV-infected individuals
  3. aLogistic regression model, adjusted for gender, age, and routes of infection
  4. bCochran–Armitage trend test
  5. Bold type indicates statistically significant results