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Table 3 Stratified analysis of rs1535045 and rs1883832 among control, spontaneous clearance and persistent infection groups

From: CD40 polymorphisms were associated with HCV infection susceptibility among Chinese population

SNPs Allele Subgroups Group (B + C)/Group A
OR(95%CI)a P a P b
rs1535045 C/T Age
<50 1.417 (0.973-2.064) 0.069 0.787
≥50 1.323 (0.955-1.832) 0.092
Gender
male 1.240 (0.764-1.652) 0.551 0.158
female 1.639 (1.181-1.274) 0.003
Routes of infection
HD 1.285 (0.684-2.413) 0.436 0.479
Drug user 0.985 (0.607-1.598) 0.951
PBD 1.418 (1.013-1.985) 0.042
rs1883832 C/T Age
<50 1.485 (1.020-2.162) 0.039 0.572
≥50 1.297 (0.979-1.719) 0.070
Gender
male 1.532 (1.077-2.180) 0.018 0.344
female 1.228 (0.917-1.646) 0.168
Routes of infection
HD 2.042 (1.225-3.404) 0.006 0.066
Drug user 1.836 (1.021-3.304) 0.043
PBD 1.111 (0.839 -1.471) 0.168
  1. Abbreviations: CI confidence interval, HD hemodialysis, PBD paid blood donors, OR odds ratio
  2. Group A: controls; Group B: spontaneous clearance subjects; Group C: persistent infection patients. Group (B + C): HCV-infected individuals
  3. a The P value, OR and 95% CIs of group (B + C) versus Group A were calculated on the basis of the binary logistic regression model, adjusted by gender, age and routes of infection in recessive model (TT versus [TC + CC])
  4. b The P value for the heterogeneity test
  5. Bold type indicates statistically significant results