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Table 8 Performance of Gene expert and LPA test as compared to DST in detecting RIF resistance

From: Comparison of GeneXpert and line probe assay for detection of Mycobacterium tuberculosis and rifampicin-mono resistance at the National Tuberculosis Reference Laboratory, Kenya

 

Sensitivity

Specificity

Predictive values

Kappa

Positive

Negative

GeneXpert

62.5 (24.5–91.5)

96.6 (90.3–99.3)

62.5 (32.7–85.1)

96.6 (92.0 98.6)

0.59 (P < 0.01)

LPA

90.0 (55.5–99.8)

99.1 (95.0–100)

90.0 (55.9–98.5)

99.1 (94.4–99.9)

0.89 (P < 0.01)